4-(3-Methoxyphenoxy)butyric acid

4-(3-Methoxyphenoxy)butyric acid

In the title compound, C11H14O4, an intermediate for the synthesis of a new kind of estrogen receptor modulator, all non-H atoms lie on a common plane (r.m.s. deviation = 0.0472 Å). All C—C bonds in the side chain are in a trans conformation, and the hydroxyl...

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Bibliographic Details
Main Authors: Julia Heilmann-Brohl, Gérard Jaouen, Michael Bolte
Format: Article
Language:English
Published: International Union of Crystallography 2009-04-01
Series:Acta Crystallographica Section E
Online Access:http://scripts.iucr.org/cgi-bin/paper?S1600536809008186
Description
Summary:In the title compound, C11H14O4, an intermediate for the synthesis of a new kind of estrogen receptor modulator, all non-H atoms lie on a common plane (r.m.s. deviation = 0.0472 Å). All C—C bonds in the side chain are in a trans conformation, and the hydroxyl group is also trans to the methylene chain. In the crystal structure, molecules form centrosymmetric dimers showing a head-to-head arrangement which is stabilized by O—H...O hydrogen bonds. A weak C—H...O contact is also present.
ISSN:1600-5368

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