Tyrosine kinase chromosomal translocations mediate distinct and overlapping gene regulation events

Tyrosine kinase chromosomal translocations mediate distinct and overlapping gene regulation events

<p>Abstract</p> <p>Background</p> <p>Leukemia is a heterogeneous disease commonly associated with recurrent chromosomal translocations that involve tyrosine kinases including BCR-ABL, TEL-PDGFRB and TEL-JAK2. Most studies on the activated tyrosine kinases have focused o...

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Bibliographic Details
Main Authors:	Kim Hani, Gillis Lisa C, Jarvis Jordan D, Yang Stuart, Huang Kai, Der Sandy, Barber Dwayne L
Format:	Article
Language:	English
Published:	BMC 2011-12-01
Series:	BMC Cancer
Online Access:	http://www.biomedcentral.com/1471-2407/11/528

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