Tyrosine kinase chromosomal translocations mediate distinct and overlapping gene regulation events
<p>Abstract</p> <p>Background</p> <p>Leukemia is a heterogeneous disease commonly associated with recurrent chromosomal translocations that involve tyrosine kinases including BCR-ABL, TEL-PDGFRB and TEL-JAK2. Most studies on the activated tyrosine kinases have focused o...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2011-12-01
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Series: | BMC Cancer |
Online Access: | http://www.biomedcentral.com/1471-2407/11/528 |