PEPTIC ULCER DISEASE: PATHOGENESIS AND DIAGNOSIS

• Main Authors: Zubair Anwar, Qurat E Noor Baig, Aqeela Khurshid, Adeela Khurshid, Iqbal Ahmad
• Format: Article
• Language: English
• Published: Baqai University Press 2015-06-01
• Series: Baqai Journal of Health Sciences
• Subjects: Peptic ulcer disease; Helicobacter pylori; diagnosis; invasive techniques; non-invasive techniques
• Online Access: http://www.baqaiassets.com/bjhs//admin/articlefiles/1467269015upl0.pdf

Helicobacter pylori is a gram-negative bacteria which forms colonies in gastric mucosa and is responsible for peptic ulcer diseases (PUDs). The present review deals with the strategies employed in the diagnosis of H. pylori infection. The diagnostic techniques for H. pylori infection are categorized into invasive and non-invasive. The invasive techniques include endoscopy, histological studies, culture and rapid urease test whereas 13C-urea breath test, stool antigen test, blood test, serology and PCR are included in non-invasive techniques. A brief outline of these techniques with their selection criteria has been discussed in this review.