Novel Fluorescent Mitochondria-Targeted Probe MitoCLox Reports Lipid Peroxidation in Response to Oxidative Stress In Vivo

Novel Fluorescent Mitochondria-Targeted Probe MitoCLox Reports Lipid Peroxidation in Response to Oxidative Stress In Vivo

A new mitochondria-targeted probe MitoCLox was designed as a starting compound for a series of probes sensitive to cardiolipin (CL) peroxidation. Fluorescence microscopy reported selective accumulation of MitoCLox in mitochondria of diverse living cell cultures and its oxidation under stress conditi...

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Bibliographic Details
Main Authors:	Konstantin G. Lyamzaev, Alisa A. Panteleeva, Anna A. Karpukhina, Ivan I. Galkin, Ekatherina N. Popova, Olga Yu. Pletjushkina, Bettina Rieger, Karin B. Busch, Armen Y. Mulkidjanian, Boris V. Chernyak
Format:	Article
Language:	English
Published:	Hindawi Limited 2020-01-01
Series:	Oxidative Medicine and Cellular Longevity
Online Access:	http://dx.doi.org/10.1155/2020/3631272

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