TDP-43, an ALS linked protein, regulates fat deposition and glucose homeostasis.

TDP-43, an ALS linked protein, regulates fat deposition and glucose homeostasis.

The identification of proteins which determine fat and lean body mass composition is critical to better understanding and treating human obesity. TDP-43 is a well-conserved RNA-binding protein known to regulate alternative splicing and recently implicated in the pathogenesis of amyotrophic lateral s...

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Bibliographic Details
Main Authors:	Nancy R Stallings, Krishna Puttaparthi, Katherine J Dowling, Christina M Luther, Dennis K Burns, Kathryn Davis, Jeffrey L Elliott
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2013-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC3742534?pdf=render

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