THE COMPOSITION OF THE PANCREATIC DUCTAL SECRETION IN CHRONIC PANCREATITIS INFLUENCE OF ALCOHOLIC ETIOLOGY
The purpose of the review is to provide an analysis of current scientific information on changes in the composition of the ductal secretion of the pancreas in chronic alcoholic pancreatitis. It has been shown that the toxic effect of alcohol at the cellular level is manifested primarily by the insuf...
Main Author: | |
---|---|
Format: | Article |
Language: | Belarusian |
Published: |
Grodno State Medical University
2019-11-01
|
Series: | Žurnal Grodnenskogo Gosudarstvennogo Medicinskogo Universiteta |
Subjects: | |
Online Access: | http://journal-grsmu.by/index.php/ojs/article/view/2449 |
id |
doaj-831cc8484615401093785a97d344b607 |
---|---|
record_format |
Article |
spelling |
doaj-831cc8484615401093785a97d344b6072020-11-24T21:51:05ZbelGrodno State Medical University Žurnal Grodnenskogo Gosudarstvennogo Medicinskogo Universiteta2221-87852413-01092019-11-0117549549910.25298/2221-8785-2019-17-5-495-499THE COMPOSITION OF THE PANCREATIC DUCTAL SECRETION IN CHRONIC PANCREATITIS INFLUENCE OF ALCOHOLIC ETIOLOGYMozheiko L. A.0Grodno State Medical UniversityThe purpose of the review is to provide an analysis of current scientific information on changes in the composition of the ductal secretion of the pancreas in chronic alcoholic pancreatitis. It has been shown that the toxic effect of alcohol at the cellular level is manifested primarily by the insufficient secretion of water and carbonates by the cells of small ducts. The crucial role of dysfunction of CFTR channels in these disorders is considered. Possible mechanisms of participation of trypsin, lactoferrin, lithostatine and calcium in precipitation and stone formation are discussed.http://journal-grsmu.by/index.php/ojs/article/view/2449pancreasductal secretionchronic alcoholic pancreatitis |
collection |
DOAJ |
language |
Belarusian |
format |
Article |
sources |
DOAJ |
author |
Mozheiko L. A. |
spellingShingle |
Mozheiko L. A. THE COMPOSITION OF THE PANCREATIC DUCTAL SECRETION IN CHRONIC PANCREATITIS INFLUENCE OF ALCOHOLIC ETIOLOGY Žurnal Grodnenskogo Gosudarstvennogo Medicinskogo Universiteta pancreas ductal secretion chronic alcoholic pancreatitis |
author_facet |
Mozheiko L. A. |
author_sort |
Mozheiko L. A. |
title |
THE COMPOSITION OF THE PANCREATIC DUCTAL SECRETION IN CHRONIC PANCREATITIS INFLUENCE OF ALCOHOLIC ETIOLOGY |
title_short |
THE COMPOSITION OF THE PANCREATIC DUCTAL SECRETION IN CHRONIC PANCREATITIS INFLUENCE OF ALCOHOLIC ETIOLOGY |
title_full |
THE COMPOSITION OF THE PANCREATIC DUCTAL SECRETION IN CHRONIC PANCREATITIS INFLUENCE OF ALCOHOLIC ETIOLOGY |
title_fullStr |
THE COMPOSITION OF THE PANCREATIC DUCTAL SECRETION IN CHRONIC PANCREATITIS INFLUENCE OF ALCOHOLIC ETIOLOGY |
title_full_unstemmed |
THE COMPOSITION OF THE PANCREATIC DUCTAL SECRETION IN CHRONIC PANCREATITIS INFLUENCE OF ALCOHOLIC ETIOLOGY |
title_sort |
composition of the pancreatic ductal secretion in chronic pancreatitis influence of alcoholic etiology |
publisher |
Grodno State Medical University |
series |
Žurnal Grodnenskogo Gosudarstvennogo Medicinskogo Universiteta |
issn |
2221-8785 2413-0109 |
publishDate |
2019-11-01 |
description |
The purpose of the review is to provide an analysis of current scientific information on changes in the composition of the ductal secretion of the pancreas in chronic alcoholic pancreatitis. It has been shown that the toxic effect of alcohol at the cellular level is manifested primarily by the insufficient secretion of water and carbonates by the cells of small ducts. The crucial role of dysfunction of CFTR channels in these disorders is considered. Possible mechanisms of participation of trypsin, lactoferrin, lithostatine and calcium in precipitation and stone formation are discussed. |
topic |
pancreas ductal secretion chronic alcoholic pancreatitis |
url |
http://journal-grsmu.by/index.php/ojs/article/view/2449 |
work_keys_str_mv |
AT mozheikola thecompositionofthepancreaticductalsecretioninchronicpancreatitisinfluenceofalcoholicetiology AT mozheikola compositionofthepancreaticductalsecretioninchronicpancreatitisinfluenceofalcoholicetiology |
_version_ |
1725880615196164096 |