THE COMPOSITION OF THE PANCREATIC DUCTAL SECRETION IN CHRONIC PANCREATITIS INFLUENCE OF ALCOHOLIC ETIOLOGY

The purpose of the review is to provide an analysis of current scientific information on changes in the composition of the ductal secretion of the pancreas in chronic alcoholic pancreatitis. It has been shown that the toxic effect of alcohol at the cellular level is manifested primarily by the insuf...

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Main Author: Mozheiko L. A.
Format: Article
Language:Belarusian
Published: Grodno State Medical University 2019-11-01
Series:Žurnal Grodnenskogo Gosudarstvennogo Medicinskogo Universiteta
Subjects:
Online Access:http://journal-grsmu.by/index.php/ojs/article/view/2449
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spelling doaj-831cc8484615401093785a97d344b6072020-11-24T21:51:05ZbelGrodno State Medical University Žurnal Grodnenskogo Gosudarstvennogo Medicinskogo Universiteta2221-87852413-01092019-11-0117549549910.25298/2221-8785-2019-17-5-495-499THE COMPOSITION OF THE PANCREATIC DUCTAL SECRETION IN CHRONIC PANCREATITIS INFLUENCE OF ALCOHOLIC ETIOLOGYMozheiko L. A.0Grodno State Medical UniversityThe purpose of the review is to provide an analysis of current scientific information on changes in the composition of the ductal secretion of the pancreas in chronic alcoholic pancreatitis. It has been shown that the toxic effect of alcohol at the cellular level is manifested primarily by the insufficient secretion of water and carbonates by the cells of small ducts. The crucial role of dysfunction of CFTR channels in these disorders is considered. Possible mechanisms of participation of trypsin, lactoferrin, lithostatine and calcium in precipitation and stone formation are discussed.http://journal-grsmu.by/index.php/ojs/article/view/2449pancreasductal secretionchronic alcoholic pancreatitis
collection DOAJ
language Belarusian
format Article
sources DOAJ
author Mozheiko L. A.
spellingShingle Mozheiko L. A.
THE COMPOSITION OF THE PANCREATIC DUCTAL SECRETION IN CHRONIC PANCREATITIS INFLUENCE OF ALCOHOLIC ETIOLOGY
Žurnal Grodnenskogo Gosudarstvennogo Medicinskogo Universiteta
pancreas
ductal secretion
chronic alcoholic pancreatitis
author_facet Mozheiko L. A.
author_sort Mozheiko L. A.
title THE COMPOSITION OF THE PANCREATIC DUCTAL SECRETION IN CHRONIC PANCREATITIS INFLUENCE OF ALCOHOLIC ETIOLOGY
title_short THE COMPOSITION OF THE PANCREATIC DUCTAL SECRETION IN CHRONIC PANCREATITIS INFLUENCE OF ALCOHOLIC ETIOLOGY
title_full THE COMPOSITION OF THE PANCREATIC DUCTAL SECRETION IN CHRONIC PANCREATITIS INFLUENCE OF ALCOHOLIC ETIOLOGY
title_fullStr THE COMPOSITION OF THE PANCREATIC DUCTAL SECRETION IN CHRONIC PANCREATITIS INFLUENCE OF ALCOHOLIC ETIOLOGY
title_full_unstemmed THE COMPOSITION OF THE PANCREATIC DUCTAL SECRETION IN CHRONIC PANCREATITIS INFLUENCE OF ALCOHOLIC ETIOLOGY
title_sort composition of the pancreatic ductal secretion in chronic pancreatitis influence of alcoholic etiology
publisher Grodno State Medical University
series Žurnal Grodnenskogo Gosudarstvennogo Medicinskogo Universiteta
issn 2221-8785
2413-0109
publishDate 2019-11-01
description The purpose of the review is to provide an analysis of current scientific information on changes in the composition of the ductal secretion of the pancreas in chronic alcoholic pancreatitis. It has been shown that the toxic effect of alcohol at the cellular level is manifested primarily by the insufficient secretion of water and carbonates by the cells of small ducts. The crucial role of dysfunction of CFTR channels in these disorders is considered. Possible mechanisms of participation of trypsin, lactoferrin, lithostatine and calcium in precipitation and stone formation are discussed.
topic pancreas
ductal secretion
chronic alcoholic pancreatitis
url http://journal-grsmu.by/index.php/ojs/article/view/2449
work_keys_str_mv AT mozheikola thecompositionofthepancreaticductalsecretioninchronicpancreatitisinfluenceofalcoholicetiology
AT mozheikola compositionofthepancreaticductalsecretioninchronicpancreatitisinfluenceofalcoholicetiology
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