The Relation between Sarcopenia and Mortality in Patients at Intensive Care Unit

Background and Aim. Psoas muscle area (PMA) can reflect the status of skeletal muscle in the whole body. It has been also reported that decreased PMA was associated with postoperative mortality or morbidity after several surgical procedures. In this study, we aimed to investigate the relation betwee...

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Main Authors: Mehmet Toptas, Mazhar Yalcin, İbrahim Akkoc, Eren Demir, Cagatay Metin, Yildiray Savas, Muhsin Kalyoncuoglu, Mehmet Mustafa Can
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2018/5263208
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spelling doaj-830e6e783ab149e683c33225cb1231352020-11-25T00:02:57ZengHindawi LimitedBioMed Research International2314-61332314-61412018-01-01201810.1155/2018/52632085263208The Relation between Sarcopenia and Mortality in Patients at Intensive Care UnitMehmet Toptas0Mazhar Yalcin1İbrahim Akkoc2Eren Demir3Cagatay Metin4Yildiray Savas5Muhsin Kalyoncuoglu6Mehmet Mustafa Can7Department of Anesthesiology, Haseki Training and Research Hospital, Istanbul, TurkeyDepartment of Radiology, Haseki Training and Research Hospital, Istanbul, TurkeyDepartment of Anesthesiology, Haseki Training and Research Hospital, Istanbul, TurkeyDepartment of Anesthesiology, Haseki Training and Research Hospital, Istanbul, TurkeyDepartment of Anesthesiology, Haseki Training and Research Hospital, Istanbul, TurkeyDepartment of Radiology, Haseki Training and Research Hospital, Istanbul, TurkeyDepartment of Cardiology, Haseki Training and Research Hospital, Istanbul, TurkeyDepartment of Cardiology, Haseki Training and Research Hospital, Istanbul, TurkeyBackground and Aim. Psoas muscle area (PMA) can reflect the status of skeletal muscle in the whole body. It has been also reported that decreased PMA was associated with postoperative mortality or morbidity after several surgical procedures. In this study, we aimed to investigate the relation between PMA and mortality in all age groups in intensive care unit (UNIT). Materials and Method. The study consists of 362 consecutive patients. The demographic characteristics of patients, indications for ICU hospitalization, laboratory parameters, and clinical parameters consist of mortality and length of stay, and surgery history was obtained from intensive care archive records. Results. The mean age was 61.2±18.2 years, and the percentage of female was 33.3%. The mean duration of stay was 10.3±24.4 days. Exitus ratio, partial healing, and healing were 25%, 70%, and 5%, respectively. The mean right, left, and total PMA were 8.7±3.6, 8.9±3.4, and 17.6±6.9, respectively. The left and total PMA averages of the nonoperation patients were statistically significantly lower (p=0.021  p=0.043). The mean PMA between the ex and recovered patients were statistically significantly lower (p=0.001, p=0.001, p<0.001). Dyspnoea, renal insufficiency, COPD, transfusion rate, operation rate, ventilator needy, and mean duration of hospitalization were statistically significant higher in patients with exitus. There is a significant difference in operation types, anesthesia type, and clinic rates. Conclusion. Our data suggest that sarcopenia can be used to risk stratification in ICU patients. Future studies may use this technique to individualize postoperative interventions that may reduce the risk for an adverse discharge disposition related to critical illness, such as early mobilization, optimized nutritional support, and reduction of sedation and opioid dose.http://dx.doi.org/10.1155/2018/5263208
collection DOAJ
language English
format Article
sources DOAJ
author Mehmet Toptas
Mazhar Yalcin
İbrahim Akkoc
Eren Demir
Cagatay Metin
Yildiray Savas
Muhsin Kalyoncuoglu
Mehmet Mustafa Can
spellingShingle Mehmet Toptas
Mazhar Yalcin
İbrahim Akkoc
Eren Demir
Cagatay Metin
Yildiray Savas
Muhsin Kalyoncuoglu
Mehmet Mustafa Can
The Relation between Sarcopenia and Mortality in Patients at Intensive Care Unit
BioMed Research International
author_facet Mehmet Toptas
Mazhar Yalcin
İbrahim Akkoc
Eren Demir
Cagatay Metin
Yildiray Savas
Muhsin Kalyoncuoglu
Mehmet Mustafa Can
author_sort Mehmet Toptas
title The Relation between Sarcopenia and Mortality in Patients at Intensive Care Unit
title_short The Relation between Sarcopenia and Mortality in Patients at Intensive Care Unit
title_full The Relation between Sarcopenia and Mortality in Patients at Intensive Care Unit
title_fullStr The Relation between Sarcopenia and Mortality in Patients at Intensive Care Unit
title_full_unstemmed The Relation between Sarcopenia and Mortality in Patients at Intensive Care Unit
title_sort relation between sarcopenia and mortality in patients at intensive care unit
publisher Hindawi Limited
series BioMed Research International
issn 2314-6133
2314-6141
publishDate 2018-01-01
description Background and Aim. Psoas muscle area (PMA) can reflect the status of skeletal muscle in the whole body. It has been also reported that decreased PMA was associated with postoperative mortality or morbidity after several surgical procedures. In this study, we aimed to investigate the relation between PMA and mortality in all age groups in intensive care unit (UNIT). Materials and Method. The study consists of 362 consecutive patients. The demographic characteristics of patients, indications for ICU hospitalization, laboratory parameters, and clinical parameters consist of mortality and length of stay, and surgery history was obtained from intensive care archive records. Results. The mean age was 61.2±18.2 years, and the percentage of female was 33.3%. The mean duration of stay was 10.3±24.4 days. Exitus ratio, partial healing, and healing were 25%, 70%, and 5%, respectively. The mean right, left, and total PMA were 8.7±3.6, 8.9±3.4, and 17.6±6.9, respectively. The left and total PMA averages of the nonoperation patients were statistically significantly lower (p=0.021  p=0.043). The mean PMA between the ex and recovered patients were statistically significantly lower (p=0.001, p=0.001, p<0.001). Dyspnoea, renal insufficiency, COPD, transfusion rate, operation rate, ventilator needy, and mean duration of hospitalization were statistically significant higher in patients with exitus. There is a significant difference in operation types, anesthesia type, and clinic rates. Conclusion. Our data suggest that sarcopenia can be used to risk stratification in ICU patients. Future studies may use this technique to individualize postoperative interventions that may reduce the risk for an adverse discharge disposition related to critical illness, such as early mobilization, optimized nutritional support, and reduction of sedation and opioid dose.
url http://dx.doi.org/10.1155/2018/5263208
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