A Practical Review of the Emerging Direct Anticoagulants, Laboratory Monitoring, and Reversal Agents

A Practical Review of the Emerging Direct Anticoagulants, Laboratory Monitoring, and Reversal Agents

Millions of patients in the United States use anticoagulation for a variety of indications, such as the prevention of stroke in those with atrial fibrillation (AF) and the treatment and prevention of venous thrombosis. For over six decades warfarin was the only available oral anticoagulant, but now...

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Main Authors: Stephanie A. Joppa, Justin Salciccioli, Jill Adamski, Salma Patel, Waldemar Wysokinski, Robert McBane, Farah Al-Saffar, Heidi Esser, Fadi Shamoun
Format: Article
Language:English
Published: MDPI AG 2018-02-01
Series:Journal of Clinical Medicine
Subjects:
anticoagulants
serum levels
reversal agents
Online Access:http://www.mdpi.com/2077-0383/7/2/29
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spelling doaj-830b44d3faa147838464c729d22a08d82020-11-24T22:54:13ZengMDPI AGJournal of Clinical Medicine2077-03832018-02-01722910.3390/jcm7020029jcm7020029A Practical Review of the Emerging Direct Anticoagulants, Laboratory Monitoring, and Reversal AgentsStephanie A. Joppa0Justin Salciccioli1Jill Adamski2Salma Patel3Waldemar Wysokinski4Robert McBane5Farah Al-Saffar6Heidi Esser7Fadi Shamoun8Department of Cardiology, Mayo Clinic, Phoenix, AZ 85054, USAWhipps Cross University Hospital, London E11 1NR, UKDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Phoenix, AZ 85054, USACenter for Sleep Medicine, Mayo Clinic, Rochester, MN 55905, USADepartment of Cardiology, Mayo Clinic, Rochester, MN 55905, USACenter for Sleep Medicine, Mayo Clinic, Rochester, MN 55905, USADepartment of Cardiology, Mayo Clinic, Phoenix, AZ 85054, USAMidwestern University, Glendale, AZ 85308, USADepartment of Cardiology, Mayo Clinic, Phoenix, AZ 85054, USAMillions of patients in the United States use anticoagulation for a variety of indications, such as the prevention of stroke in those with atrial fibrillation (AF) and the treatment and prevention of venous thrombosis. For over six decades warfarin was the only available oral anticoagulant, but now several DOACs are available and their use has become more prevalent in recent years. In spite of this increased use, many physicians remain reluctant to prescribe DOACs due to concerns about bleeding and reversibility.http://www.mdpi.com/2077-0383/7/2/29anticoagulantsserum levelsreversal agents
collection DOAJ
language English
format Article
sources DOAJ
author Stephanie A. Joppa
Justin Salciccioli
Jill Adamski
Salma Patel
Waldemar Wysokinski
Robert McBane
Farah Al-Saffar
Heidi Esser
Fadi Shamoun
spellingShingle Stephanie A. Joppa
Justin Salciccioli
Jill Adamski
Salma Patel
Waldemar Wysokinski
Robert McBane
Farah Al-Saffar
Heidi Esser
Fadi Shamoun
A Practical Review of the Emerging Direct Anticoagulants, Laboratory Monitoring, and Reversal Agents
Journal of Clinical Medicine
anticoagulants
serum levels
reversal agents
author_facet Stephanie A. Joppa
Justin Salciccioli
Jill Adamski
Salma Patel
Waldemar Wysokinski
Robert McBane
Farah Al-Saffar
Heidi Esser
Fadi Shamoun
author_sort Stephanie A. Joppa
title A Practical Review of the Emerging Direct Anticoagulants, Laboratory Monitoring, and Reversal Agents
title_short A Practical Review of the Emerging Direct Anticoagulants, Laboratory Monitoring, and Reversal Agents
title_full A Practical Review of the Emerging Direct Anticoagulants, Laboratory Monitoring, and Reversal Agents
title_fullStr A Practical Review of the Emerging Direct Anticoagulants, Laboratory Monitoring, and Reversal Agents
title_full_unstemmed A Practical Review of the Emerging Direct Anticoagulants, Laboratory Monitoring, and Reversal Agents
title_sort practical review of the emerging direct anticoagulants, laboratory monitoring, and reversal agents
publisher MDPI AG
series Journal of Clinical Medicine
issn 2077-0383
publishDate 2018-02-01
description Millions of patients in the United States use anticoagulation for a variety of indications, such as the prevention of stroke in those with atrial fibrillation (AF) and the treatment and prevention of venous thrombosis. For over six decades warfarin was the only available oral anticoagulant, but now several DOACs are available and their use has become more prevalent in recent years. In spite of this increased use, many physicians remain reluctant to prescribe DOACs due to concerns about bleeding and reversibility.
topic anticoagulants
serum levels
reversal agents
url http://www.mdpi.com/2077-0383/7/2/29
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