Hepatitis C virus infection and related liver disease: the quest for the best animal model

Hepatitis C virus infection and related liver disease: the quest for the best animal model

Hepatitis C virus (HCV) is a major cause of cirrhosis and hepatocellular carcinoma (HCC) making the virus the most common cause of liver failure and transplantation. HCV is estimated to chronically affect 130 million individuals and to lead to more than 350,000 deaths per year worldwide. A vaccine i...

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Bibliographic Details
Main Authors: Laurent eMailly, Eric eRobinet, Philip eMeuleman, Thomas F. Baumert, Mirjam B. Zeisel
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-07-01
Series:Frontiers in Microbiology
Subjects:
Animal Models
antivirals
Hepatitis C virus
Hepatocellular Carcinoma
Liver disease
immunocompetent mouse model
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2013.00212/full

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