Synthesis of Chlorinated Tetracyclic Compounds and Testing for Their Potential Antidepressant Effect in Mice

Synthesis of Chlorinated Tetracyclic Compounds and Testing for Their Potential Antidepressant Effect in Mice

The synthesis of the tetracyclic compounds 1-(4,5-dichloro-9,10-dihydro-9,10-ethanoanthracen-11-yl)-N-methylmethanamine (5) and 1-(1,8-dichloro-9,10-dihydro-9,10-ethanoanthracen-11-yl)-N-methylmethanamine (6) as a homologue of the anxiolytic and antidepressant drugs benzoctamine and maprotiline were...

Full description

Bibliographic Details
Main Authors: Usama Karama, Mujeeb A. Sultan, Abdulrahman I. Almansour, Kamal Eldin El-Taher
Format: Article
Language:English
Published: MDPI AG 2016-01-01
Series:Molecules
Subjects:
chlorinated tetracyclic
antidepressants
synthesis
forced swimming test
Online Access:http://www.mdpi.com/1420-3049/21/1/61

Internet

http://www.mdpi.com/1420-3049/21/1/61

Similar Items