Outcomes of Retinal Detachment Surgery in Eyes with Chorioretinal Coloboma

• Main Authors: Alireza Ramezani, Mohammad-Hossein Dehghan, Ahmad Rostami, Hamid Ahmadieh, Morteza Entezari, Masoud Soheilian, Mohsen Azarmina, Siamak Moradian, Mehdi Yaseri
• Format: Article
• Language: English
• Published: Knowledge E 2010-01-01
• Series: Journal of Ophthalmic & Vision Research
• Subjects: Coloboma; Retinal Detachment; Vitrectomy; Scleral Buckle; Intraocular Pressure
• Online Access: http://www.jovr.org/article.asp?issn=2008-322X;year=2010;volume=5;issue=4;spage=240;epage=245;aulast=Ramezani

Purpose: To report the anatomical and functional outcomes of surgery for retinal detachment associated with chorioretinal colobomas. Methods: In this retrospective interventional case series, 28 eyes of 28 patients (including 18 male subjects) who had undergone surgery for retinal detachment associated with chorioretinal colobomas were evaluated regarding the type of intervention, final visual acuity and anatomical outcomes, as well as complications. Cases with less than 3 months of follow-up were excluded. Results: Primary surgery included vitrectomy in 25 (89.3%) and scleral buckling in 3 (10.7%) eyes. The internal tamponade used in eyes undergoing vitrectomy was silicone oil in 23 (92%) eyes and 20% sulfur hexafluoride (SF6) in 2 (8%) eyes. Silicone oil was removed in 11 eyes (45.8%). The mean number of operations per eye was 1.57±0.74, mean follow-up was 40±36 months, and the retina remained attached in 26 eyes (92.9%) at final follow-up. Mean preoperative visual acuity was 2.33±0.55 (range, 1.15-2.9) logMAR which significantly improved to 1.72±0.9 (range, 0.09-3.1) logMAR postoperatively (P < 0.001), however, final median visual acuity was counting fingers at 2 m. The most common complications were cataracts (100%) and ocular hypertension (46.4%). Conclusion: The most prevalent surgical procedure for treatment of retinal detachment associated with chorioretinal coloboma was pars plana vitrectomy and the most frequently used tamponade was silicone oil. Although anatomical success was satisfactory, functional outcomes were not encouraging which reflects the complexity of the condition and associated abnormalities.