Pleiotropic Activity of Metformin and Its Sulfonamide Derivatives on Vascular and Platelet Haemostasis

Pleiotropic Activity of Metformin and Its Sulfonamide Derivatives on Vascular and Platelet Haemostasis

As type 2 diabetes mellitus (T2DM) predisposes patients to endothelial cell injury and dysfunction, improvement of vascular function should be an important target for therapy. The aim of this study was to evaluate the effects of metformin, its sulfenamide and sulfonamide derivatives on selected para...

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Bibliographic Details
Main Authors: Magdalena Markowicz-Piasecka, Kristiina M. Huttunen, Adrianna Sadkowska, Joanna Sikora
Format: Article
Language:English
Published: MDPI AG 2019-12-01
Series:Molecules
Subjects:
endothelium
vascular smooth muscle
metformin
platelet
biguanides
Online Access:https://www.mdpi.com/1420-3049/25/1/125

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