Dysregulated B cell expression of RANKL and OPG correlates with loss of bone mineral density in HIV infection.

Dysregulated B cell expression of RANKL and OPG correlates with loss of bone mineral density in HIV infection.

HIV infection is associated with high rates of osteopenia and osteoporosis, but the mechanisms involved are unclear. We recently reported that bone loss in the HIV transgenic rat model was associated with upregulation of B cell expression of the key osteoclastogenic cytokine receptor-activator of NF...

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Bibliographic Details
Main Authors: Kehmia Titanji, Aswani Vunnava, Anandi N Sheth, Cecile Delille, Jeffrey L Lennox, Sara E Sanford, Antonina Foster, Andrea Knezevic, Kirk A Easley, M Neale Weitzmann, Ighovwerha Ofotokun
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-10-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1004497

Internet

https://doi.org/10.1371/journal.ppat.1004497

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