THE ROLE OF GENETIC DETERMINANTS AND DISORDERS IN SYSTEMIC AND LOCAL IMMUNITY IN THE ETIOLOGY AND PATHOGENESIS OF HERPETIC ECZEMA (KAPOSI'S ECZEMA)

THE ROLE OF GENETIC DETERMINANTS AND DISORDERS IN SYSTEMIC AND LOCAL IMMUNITY IN THE ETIOLOGY AND PATHOGENESIS OF HERPETIC ECZEMA (KAPOSI'S ECZEMA)

This review presents an analysis of the literature data on the etiology and pathogenesis  of Herpetic Eczema (Kaposi's Eczema). Modern views on the complex genetic and phenotypic determinants of disease, reflecting the complex interactions between the skin and the immune system. Along with the...

Full description

Bibliographic Details
Main Authors: A. S. Stadnikova, O. B Tamrazova, T. A. Chebotareva
Format: Article
Language:Russian
Published: LLC "Diagnostics and Vaccines" 2016-09-01
Series:Detskie Infekcii (Moskva)
Subjects:
herpetic eczema
kaposi's eczema
herpes simplex virus
atopic dermatitis
children
immunity
Online Access:https://detinf.elpub.ru/jour/article/view/245
id doaj-82ce8a2e7ce24b48b706d5b741e2afd1
record_format Article
spelling doaj-82ce8a2e7ce24b48b706d5b741e2afd12021-08-02T09:19:50ZrusLLC "Diagnostics and Vaccines"Detskie Infekcii (Moskva)2072-81072016-09-01153424510.22627/2072-8107-2016-15-3-42-45239THE ROLE OF GENETIC DETERMINANTS AND DISORDERS IN SYSTEMIC AND LOCAL IMMUNITY IN THE ETIOLOGY AND PATHOGENESIS OF HERPETIC ECZEMA (KAPOSI'S ECZEMA)A. S. Stadnikova0O. B Tamrazova1T. A. Chebotareva2Moscow Scientific-Practical Center of dermatology and cosmetology, MoscowRussian University of Peoples' Friendship; Children's City Clinical Hospital them Z.A. Bashlyaevoy, MoscowRussian Medical Academy of Postgraduate Education of the Ministry of Health of Russia, MoscowThis review presents an analysis of the literature data on the etiology and pathogenesis  of Herpetic Eczema (Kaposi's Eczema). Modern views on the complex genetic and phenotypic determinants of disease, reflecting the complex interactions between the skin and the immune system. Along with the general regularities characteristic of Herpetic Eczema in sufficient detail the reasons of infringements of functioning of the epidermal skin barrier, which contribute to an easier penetration of the Herpes Simplex  Virus in the skin and its binding  to cellular receptors in the implementation of the infectious process. The effect of systemic and local immunity, namely, changes in T-cell and interferon system in the development of the pathological process.https://detinf.elpub.ru/jour/article/view/245herpetic eczemakaposi's eczemaherpes simplex virusatopic dermatitischildrenimmunity
collection DOAJ
language Russian
format Article
sources DOAJ
author A. S. Stadnikova
O. B Tamrazova
T. A. Chebotareva
spellingShingle A. S. Stadnikova
O. B Tamrazova
T. A. Chebotareva
THE ROLE OF GENETIC DETERMINANTS AND DISORDERS IN SYSTEMIC AND LOCAL IMMUNITY IN THE ETIOLOGY AND PATHOGENESIS OF HERPETIC ECZEMA (KAPOSI'S ECZEMA)
Detskie Infekcii (Moskva)
herpetic eczema
kaposi's eczema
herpes simplex virus
atopic dermatitis
children
immunity
author_facet A. S. Stadnikova
O. B Tamrazova
T. A. Chebotareva
author_sort A. S. Stadnikova
title THE ROLE OF GENETIC DETERMINANTS AND DISORDERS IN SYSTEMIC AND LOCAL IMMUNITY IN THE ETIOLOGY AND PATHOGENESIS OF HERPETIC ECZEMA (KAPOSI'S ECZEMA)
title_short THE ROLE OF GENETIC DETERMINANTS AND DISORDERS IN SYSTEMIC AND LOCAL IMMUNITY IN THE ETIOLOGY AND PATHOGENESIS OF HERPETIC ECZEMA (KAPOSI'S ECZEMA)
title_full THE ROLE OF GENETIC DETERMINANTS AND DISORDERS IN SYSTEMIC AND LOCAL IMMUNITY IN THE ETIOLOGY AND PATHOGENESIS OF HERPETIC ECZEMA (KAPOSI'S ECZEMA)
title_fullStr THE ROLE OF GENETIC DETERMINANTS AND DISORDERS IN SYSTEMIC AND LOCAL IMMUNITY IN THE ETIOLOGY AND PATHOGENESIS OF HERPETIC ECZEMA (KAPOSI'S ECZEMA)
title_full_unstemmed THE ROLE OF GENETIC DETERMINANTS AND DISORDERS IN SYSTEMIC AND LOCAL IMMUNITY IN THE ETIOLOGY AND PATHOGENESIS OF HERPETIC ECZEMA (KAPOSI'S ECZEMA)
title_sort role of genetic determinants and disorders in systemic and local immunity in the etiology and pathogenesis of herpetic eczema (kaposi's eczema)
publisher LLC "Diagnostics and Vaccines"
series Detskie Infekcii (Moskva)
issn 2072-8107
publishDate 2016-09-01
description This review presents an analysis of the literature data on the etiology and pathogenesis  of Herpetic Eczema (Kaposi's Eczema). Modern views on the complex genetic and phenotypic determinants of disease, reflecting the complex interactions between the skin and the immune system. Along with the general regularities characteristic of Herpetic Eczema in sufficient detail the reasons of infringements of functioning of the epidermal skin barrier, which contribute to an easier penetration of the Herpes Simplex  Virus in the skin and its binding  to cellular receptors in the implementation of the infectious process. The effect of systemic and local immunity, namely, changes in T-cell and interferon system in the development of the pathological process.
topic herpetic eczema
kaposi's eczema
herpes simplex virus
atopic dermatitis
children
immunity
url https://detinf.elpub.ru/jour/article/view/245
work_keys_str_mv AT asstadnikova theroleofgeneticdeterminantsanddisordersinsystemicandlocalimmunityintheetiologyandpathogenesisofherpeticeczemakaposiseczema
AT obtamrazova theroleofgeneticdeterminantsanddisordersinsystemicandlocalimmunityintheetiologyandpathogenesisofherpeticeczemakaposiseczema
AT tachebotareva theroleofgeneticdeterminantsanddisordersinsystemicandlocalimmunityintheetiologyandpathogenesisofherpeticeczemakaposiseczema
AT asstadnikova roleofgeneticdeterminantsanddisordersinsystemicandlocalimmunityintheetiologyandpathogenesisofherpeticeczemakaposiseczema
AT obtamrazova roleofgeneticdeterminantsanddisordersinsystemicandlocalimmunityintheetiologyandpathogenesisofherpeticeczemakaposiseczema
AT tachebotareva roleofgeneticdeterminantsanddisordersinsystemicandlocalimmunityintheetiologyandpathogenesisofherpeticeczemakaposiseczema
_version_ 1721235108736794624

Similar Items