Phagocytosis is coupled to the formation of phagosome-associated podosomes and a transient disruption of podosomes in human macrophages

Phagocytosis is coupled to the formation of phagosome-associated podosomes and a transient disruption of podosomes in human macrophages

Phagocytosis consists in ingestion and digestion of large particles, a process strictly dependent on actin re-organization. Using synchronized phagocytosis of IgG-coated latex beads (IgG-LB), zymosan or serum opsonized-zymosan, we report the formation of actin structures on both phagocytic cups and...

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Bibliographic Details
Main Authors: Margot Tertrais, Claire Bigot, Emmanuel Martin, Renaud Poincloux, Arnaud Labrousse, Isabelle Maridonneau-Parini
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:European Journal of Cell Biology
Subjects:
Podosome
Phagocytosis
Macrophage
Phagolysosome
Online Access:http://www.sciencedirect.com/science/article/pii/S0171933521000121

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