MicroRNA-29b Regulates the Mitochondria-Dependent Apoptotic Pathway by Targeting Bax in Doxorubicin Cardiotoxicity

MicroRNA-29b Regulates the Mitochondria-Dependent Apoptotic Pathway by Targeting Bax in Doxorubicin Cardiotoxicity

Background/Aims: Myocardial apoptosis plays an important role in doxorubicin (Dox) cardiotoxicity. MicroRNA-29 (miR-29) is suggested to function as an anti-fibrotic factor with potential therapeutic effects on cardiac fibrosis. However, it has not been shown whether there is an association between m...

Full description

Bibliographic Details
Main Authors: Xibo Jing, Jingxiao Yang, Lu Jiang, Jianghong Chen, Haiyan Wang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-07-01
Series:Cellular Physiology and Biochemistry
Subjects:
Mitochondria pathway
Doxorubicin
Cardiotoxicity
Myocardial apoptosis
MicroRNA-29b
Online Access:https://www.karger.com/Article/FullText/491896

Similar Items

Similar Items