Informative Value of the Parameters of Endotoxicosis in Patients with Diabetes Mellitus and Generalized Purulent Peritonitis

Informative Value of the Parameters of Endotoxicosis in Patients with Diabetes Mellitus and Generalized Purulent Peritonitis

The present study was undertaken to evaluate the informative value of the parameters reflecting the severity of endotoxi-cosis in the early postoperative period in diabetic patients with generalized purulent peritonitis. Sixty-six patients were examined and treated. A follow-up assessment of biochem...

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Main Authors: A. O. Girsh, V. T. Dolgikh, V. N. Lukach, V. V. Moroz, O. A. Malkov
Format: Article
Language:Russian
Published: Russian Academy of Medical Sciences 2005-12-01
Series:Obŝaâ Reanimatologiâ
Online Access:https://www.reanimatology.com/rmt/article/view/1210
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spelling doaj-82bc30dcdd8048b3816b99c683458c702021-07-28T21:21:46ZrusRussian Academy of Medical SciencesObŝaâ Reanimatologiâ1813-97792411-71102005-12-0116444810.15360/1813-9779-2005-6-44-481210Informative Value of the Parameters of Endotoxicosis in Patients with Diabetes Mellitus and Generalized Purulent PeritonitisA. O. Girsh0V. T. Dolgikh1V. N. Lukach2V. V. Moroz3O. A. Malkov4Department of Anesthesiology, Resuscitation, and Medical Emergency Care, Department of PathophysiologyDepartment of Anesthesiology, Resuscitation, and Medical Emergency Care, Department of PathophysiologyDepartment of Anesthesiology, Resuscitation, and Medical Emergency Care, Department of PathophysiologyResearch Institute of General Reanimatology, Russian Academy of Medical Sciences, MoscowDepartment of Surgery with a Anesthesiology and Resuscitation Course, Surgit State UniversityThe present study was undertaken to evaluate the informative value of the parameters reflecting the severity of endotoxi-cosis in the early postoperative period in diabetic patients with generalized purulent peritonitis. Sixty-six patients were examined and treated. A follow-up assessment of biochemical, immunological, and hemodynamic parameters has established that the serum level of procalcitonin, the level of leukocytosis, the immunoregulatory index, the content of circulating immune complexes, the scores of the SOFA scale, and minute circulatory volume are the most sensitive and specific markers of the severity of endotoxicosis. They show a low frequency of false-positive results, a high prognostic value of positive results, and a low prognostic value of negative ones.https://www.reanimatology.com/rmt/article/view/1210
collection DOAJ
language Russian
format Article
sources DOAJ
author A. O. Girsh
V. T. Dolgikh
V. N. Lukach
V. V. Moroz
O. A. Malkov
spellingShingle A. O. Girsh
V. T. Dolgikh
V. N. Lukach
V. V. Moroz
O. A. Malkov
Informative Value of the Parameters of Endotoxicosis in Patients with Diabetes Mellitus and Generalized Purulent Peritonitis
Obŝaâ Reanimatologiâ
author_facet A. O. Girsh
V. T. Dolgikh
V. N. Lukach
V. V. Moroz
O. A. Malkov
author_sort A. O. Girsh
title Informative Value of the Parameters of Endotoxicosis in Patients with Diabetes Mellitus and Generalized Purulent Peritonitis
title_short Informative Value of the Parameters of Endotoxicosis in Patients with Diabetes Mellitus and Generalized Purulent Peritonitis
title_full Informative Value of the Parameters of Endotoxicosis in Patients with Diabetes Mellitus and Generalized Purulent Peritonitis
title_fullStr Informative Value of the Parameters of Endotoxicosis in Patients with Diabetes Mellitus and Generalized Purulent Peritonitis
title_full_unstemmed Informative Value of the Parameters of Endotoxicosis in Patients with Diabetes Mellitus and Generalized Purulent Peritonitis
title_sort informative value of the parameters of endotoxicosis in patients with diabetes mellitus and generalized purulent peritonitis
publisher Russian Academy of Medical Sciences
series Obŝaâ Reanimatologiâ
issn 1813-9779
2411-7110
publishDate 2005-12-01
description The present study was undertaken to evaluate the informative value of the parameters reflecting the severity of endotoxi-cosis in the early postoperative period in diabetic patients with generalized purulent peritonitis. Sixty-six patients were examined and treated. A follow-up assessment of biochemical, immunological, and hemodynamic parameters has established that the serum level of procalcitonin, the level of leukocytosis, the immunoregulatory index, the content of circulating immune complexes, the scores of the SOFA scale, and minute circulatory volume are the most sensitive and specific markers of the severity of endotoxicosis. They show a low frequency of false-positive results, a high prognostic value of positive results, and a low prognostic value of negative ones.
url https://www.reanimatology.com/rmt/article/view/1210
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