Altered biomarkers of mucosal immunity and reduced vaginal Lactobacillus concentrations in sexually active female adolescents.

Genital secretions collected from adult women exhibit in vitro activity against herpes simplex virus (HSV) and Escherichia coli (E. coli), but prior studies have not investigated this endogenous antimicrobial activity or its mediators in adolescent females.Anti-HSV and anti-E.coli activity were quan...

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Bibliographic Details
Main Authors: Rebecca Pellett Madan, Colleen Carpenter, Tina Fiedler, Sabah Kalyoussef, Thomas C McAndrew, Shankar Viswanathan, Mimi Kim, Marla J Keller, David N Fredricks, Betsy C Herold
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3393710?pdf=render