The quality of life impact of peripheral versus central vision loss with a focus on glaucoma versus age-related macular degeneration
Keith Evans1, Simon K Law2, John Walt3, Patricia Buchholz4, Jan Hansen31Global Health Outcomes, Wolters Kluwer Health, Chester, United Kingdom; 2Jules Stein Eye Institute, Los Angeles, CA, USA; 3Global Health Outcomes Strategy and Research, Allergan Inc., Irvine, CA, USA; 4Health Economics, Pricing,...
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2009-07-01
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doaj-82b90ef6f7024ca08fab26436c5febf72020-11-25T01:36:03ZengDove Medical PressClinical Ophthalmology1177-54671177-54832009-07-012009default433445The quality of life impact of peripheral versus central vision loss with a focus on glaucoma versus age-related macular degenerationKeith EvansSimon K LawJohn Waltet alKeith Evans1, Simon K Law2, John Walt3, Patricia Buchholz4, Jan Hansen31Global Health Outcomes, Wolters Kluwer Health, Chester, United Kingdom; 2Jules Stein Eye Institute, Los Angeles, CA, USA; 3Global Health Outcomes Strategy and Research, Allergan Inc., Irvine, CA, USA; 4Health Economics, Pricing, and Reimbursement, Allergan GmbH, Ettlingen, GermanyPurpose: It is well accepted that conditions that cause central vision loss (CVL) have a negative impact on functional ability and quality of life (QoL), but the impact of diseases that cause peripheral vision loss (PVL) is less well understood. Focusing on glaucoma and age-related macular degeneration (ARMD), the effects of CVL and PVL on QoL were compared. Methods: A systematic literature review of publications reporting QoL in patients with CVL or PVL identified 87 publications using four generic (Short-Form Health Survey-36 and -12, EuroQoL EQ-5D and Sickness Impact Profile) and five vision-specific (National Eye Institute Visual Function Questionnaire-51, -39, and -25, Impact of Vision Impairment and Visual Function-14) QoL instruments; 33 and 15 publications reported QoL in ARMD and glaucoma, respectively.Results: QoL was impaired to a similar extent by diseases associated with PVL and CVL, but different domains were affected. In contrast to ARMD, mental aspects appeared to be affected more than physical aspects in patients with glaucoma.Conclusions: The differential impact upon QoL might be a function of the pathology of the diseases, for example potential for blindness and better ability to perform physical tasks due to retention of central vision may explain these observations in glaucoma.Keywords: vision loss, quality of life, glaucoma, age-related macular degeneration, diabetic macular edema, cataracts http://www.dovepress.com/the-quality-of-life-impact-of-peripheral-versus-central-vision-loss-wi-a3396 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Keith Evans Simon K Law John Walt et al |
spellingShingle |
Keith Evans Simon K Law John Walt et al The quality of life impact of peripheral versus central vision loss with a focus on glaucoma versus age-related macular degeneration Clinical Ophthalmology |
author_facet |
Keith Evans Simon K Law John Walt et al |
author_sort |
Keith Evans |
title |
The quality of life impact of peripheral versus central vision loss with a focus on glaucoma versus age-related macular degeneration |
title_short |
The quality of life impact of peripheral versus central vision loss with a focus on glaucoma versus age-related macular degeneration |
title_full |
The quality of life impact of peripheral versus central vision loss with a focus on glaucoma versus age-related macular degeneration |
title_fullStr |
The quality of life impact of peripheral versus central vision loss with a focus on glaucoma versus age-related macular degeneration |
title_full_unstemmed |
The quality of life impact of peripheral versus central vision loss with a focus on glaucoma versus age-related macular degeneration |
title_sort |
quality of life impact of peripheral versus central vision loss with a focus on glaucoma versus age-related macular degeneration |
publisher |
Dove Medical Press |
series |
Clinical Ophthalmology |
issn |
1177-5467 1177-5483 |
publishDate |
2009-07-01 |
description |
Keith Evans1, Simon K Law2, John Walt3, Patricia Buchholz4, Jan Hansen31Global Health Outcomes, Wolters Kluwer Health, Chester, United Kingdom; 2Jules Stein Eye Institute, Los Angeles, CA, USA; 3Global Health Outcomes Strategy and Research, Allergan Inc., Irvine, CA, USA; 4Health Economics, Pricing, and Reimbursement, Allergan GmbH, Ettlingen, GermanyPurpose: It is well accepted that conditions that cause central vision loss (CVL) have a negative impact on functional ability and quality of life (QoL), but the impact of diseases that cause peripheral vision loss (PVL) is less well understood. Focusing on glaucoma and age-related macular degeneration (ARMD), the effects of CVL and PVL on QoL were compared. Methods: A systematic literature review of publications reporting QoL in patients with CVL or PVL identified 87 publications using four generic (Short-Form Health Survey-36 and -12, EuroQoL EQ-5D and Sickness Impact Profile) and five vision-specific (National Eye Institute Visual Function Questionnaire-51, -39, and -25, Impact of Vision Impairment and Visual Function-14) QoL instruments; 33 and 15 publications reported QoL in ARMD and glaucoma, respectively.Results: QoL was impaired to a similar extent by diseases associated with PVL and CVL, but different domains were affected. In contrast to ARMD, mental aspects appeared to be affected more than physical aspects in patients with glaucoma.Conclusions: The differential impact upon QoL might be a function of the pathology of the diseases, for example potential for blindness and better ability to perform physical tasks due to retention of central vision may explain these observations in glaucoma.Keywords: vision loss, quality of life, glaucoma, age-related macular degeneration, diabetic macular edema, cataracts |
url |
http://www.dovepress.com/the-quality-of-life-impact-of-peripheral-versus-central-vision-loss-wi-a3396 |
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