The quality of life impact of peripheral versus central vision loss with a focus on glaucoma versus age-related macular degeneration

Keith Evans1, Simon K Law2, John Walt3, Patricia Buchholz4, Jan Hansen31Global Health Outcomes, Wolters Kluwer Health, Chester, United Kingdom; 2Jules Stein Eye Institute, Los Angeles, CA, USA; 3Global Health Outcomes Strategy and Research, Allergan Inc., Irvine, CA, USA; 4Health Economics, Pricing,...

Full description

Bibliographic Details
Main Authors: Keith Evans, Simon K Law, John Walt, et al
Format: Article
Language:English
Published: Dove Medical Press 2009-07-01
Series:Clinical Ophthalmology
Online Access:http://www.dovepress.com/the-quality-of-life-impact-of-peripheral-versus-central-vision-loss-wi-a3396
id doaj-82b90ef6f7024ca08fab26436c5febf7
record_format Article
spelling doaj-82b90ef6f7024ca08fab26436c5febf72020-11-25T01:36:03ZengDove Medical PressClinical Ophthalmology1177-54671177-54832009-07-012009default433445The quality of life impact of peripheral versus central vision loss with a focus on glaucoma versus age-related macular degenerationKeith EvansSimon K LawJohn Waltet alKeith Evans1, Simon K Law2, John Walt3, Patricia Buchholz4, Jan Hansen31Global Health Outcomes, Wolters Kluwer Health, Chester, United Kingdom; 2Jules Stein Eye Institute, Los Angeles, CA, USA; 3Global Health Outcomes Strategy and Research, Allergan Inc., Irvine, CA, USA; 4Health Economics, Pricing, and Reimbursement, Allergan GmbH, Ettlingen, GermanyPurpose: It is well accepted that conditions that cause central vision loss (CVL) have a negative impact on functional ability and quality of life (QoL), but the impact of diseases that cause peripheral vision loss (PVL) is less well understood. Focusing on glaucoma and age-related macular degeneration (ARMD), the effects of CVL and PVL on QoL were compared. Methods: A systematic literature review of publications reporting QoL in patients with CVL or PVL identified 87 publications using four generic (Short-Form Health Survey-36 and -12, EuroQoL EQ-5D and Sickness Impact Profile) and five vision-specific (National Eye Institute Visual Function Questionnaire-51, -39, and -25, Impact of Vision Impairment and Visual Function-14) QoL instruments; 33 and 15 publications reported QoL in ARMD and glaucoma, respectively.Results: QoL was impaired to a similar extent by diseases associated with PVL and CVL, but different domains were affected. In contrast to ARMD, mental aspects appeared to be affected more than physical aspects in patients with glaucoma.Conclusions: The differential impact upon QoL might be a function of the pathology of the diseases, for example potential for blindness and better ability to perform physical tasks due to retention of central vision may explain these observations in glaucoma.Keywords: vision loss, quality of life, glaucoma, age-related macular degeneration, diabetic macular edema, cataracts http://www.dovepress.com/the-quality-of-life-impact-of-peripheral-versus-central-vision-loss-wi-a3396
collection DOAJ
language English
format Article
sources DOAJ
author Keith Evans
Simon K Law
John Walt
et al
spellingShingle Keith Evans
Simon K Law
John Walt
et al
The quality of life impact of peripheral versus central vision loss with a focus on glaucoma versus age-related macular degeneration
Clinical Ophthalmology
author_facet Keith Evans
Simon K Law
John Walt
et al
author_sort Keith Evans
title The quality of life impact of peripheral versus central vision loss with a focus on glaucoma versus age-related macular degeneration
title_short The quality of life impact of peripheral versus central vision loss with a focus on glaucoma versus age-related macular degeneration
title_full The quality of life impact of peripheral versus central vision loss with a focus on glaucoma versus age-related macular degeneration
title_fullStr The quality of life impact of peripheral versus central vision loss with a focus on glaucoma versus age-related macular degeneration
title_full_unstemmed The quality of life impact of peripheral versus central vision loss with a focus on glaucoma versus age-related macular degeneration
title_sort quality of life impact of peripheral versus central vision loss with a focus on glaucoma versus age-related macular degeneration
publisher Dove Medical Press
series Clinical Ophthalmology
issn 1177-5467
1177-5483
publishDate 2009-07-01
description Keith Evans1, Simon K Law2, John Walt3, Patricia Buchholz4, Jan Hansen31Global Health Outcomes, Wolters Kluwer Health, Chester, United Kingdom; 2Jules Stein Eye Institute, Los Angeles, CA, USA; 3Global Health Outcomes Strategy and Research, Allergan Inc., Irvine, CA, USA; 4Health Economics, Pricing, and Reimbursement, Allergan GmbH, Ettlingen, GermanyPurpose: It is well accepted that conditions that cause central vision loss (CVL) have a negative impact on functional ability and quality of life (QoL), but the impact of diseases that cause peripheral vision loss (PVL) is less well understood. Focusing on glaucoma and age-related macular degeneration (ARMD), the effects of CVL and PVL on QoL were compared. Methods: A systematic literature review of publications reporting QoL in patients with CVL or PVL identified 87 publications using four generic (Short-Form Health Survey-36 and -12, EuroQoL EQ-5D and Sickness Impact Profile) and five vision-specific (National Eye Institute Visual Function Questionnaire-51, -39, and -25, Impact of Vision Impairment and Visual Function-14) QoL instruments; 33 and 15 publications reported QoL in ARMD and glaucoma, respectively.Results: QoL was impaired to a similar extent by diseases associated with PVL and CVL, but different domains were affected. In contrast to ARMD, mental aspects appeared to be affected more than physical aspects in patients with glaucoma.Conclusions: The differential impact upon QoL might be a function of the pathology of the diseases, for example potential for blindness and better ability to perform physical tasks due to retention of central vision may explain these observations in glaucoma.Keywords: vision loss, quality of life, glaucoma, age-related macular degeneration, diabetic macular edema, cataracts
url http://www.dovepress.com/the-quality-of-life-impact-of-peripheral-versus-central-vision-loss-wi-a3396
work_keys_str_mv AT keithevans thequalityoflifeimpactofperipheralversuscentralvisionlosswithafocusonglaucomaversusagerelatedmaculardegeneration
AT simonklaw thequalityoflifeimpactofperipheralversuscentralvisionlosswithafocusonglaucomaversusagerelatedmaculardegeneration
AT johnwalt thequalityoflifeimpactofperipheralversuscentralvisionlosswithafocusonglaucomaversusagerelatedmaculardegeneration
AT etal thequalityoflifeimpactofperipheralversuscentralvisionlosswithafocusonglaucomaversusagerelatedmaculardegeneration
AT keithevans qualityoflifeimpactofperipheralversuscentralvisionlosswithafocusonglaucomaversusagerelatedmaculardegeneration
AT simonklaw qualityoflifeimpactofperipheralversuscentralvisionlosswithafocusonglaucomaversusagerelatedmaculardegeneration
AT johnwalt qualityoflifeimpactofperipheralversuscentralvisionlosswithafocusonglaucomaversusagerelatedmaculardegeneration
AT etal qualityoflifeimpactofperipheralversuscentralvisionlosswithafocusonglaucomaversusagerelatedmaculardegeneration
_version_ 1725064566293921792