Successful Treatment of Diabetes in Nod Mice with Advanced Disease by Islet Isografts following Immunoregulation with Linomide (Quinoline-3-Carboxamide)

We have recently documented that oral Linomide (quinoline-3-carboxamide) prevents autoimmune insulitis, islet destruction, and diabetes in NOD mice treated at an early stage (5 wk of age) of the disease. In this report, we show that treatment of female NOD mice with advanced disease (age 23-24 wk) b...

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Bibliographic Details
Main Authors: Shimon Slavin, Lola Weiss, Xia Wenlang, David J. Gross
Format: Article
Language:English
Published: SAGE Publishing 1996-11-01
Series:Cell Transplantation
Online Access:https://doi.org/10.1177/096368979600500605