Modulation of macrophage phenotype through controlled release of interleukin-4 from gelatine coatings on titanium surfaces

Modulation of macrophage phenotype through controlled release of interleukin-4 from gelatine coatings on titanium surfaces

Pro-inflammatory phenotype (M1) macrophages initiate angiogenesis, while their prolonged activation can induce chronic inflammation. Anti-inflammatory phenotype (M2) macrophages promote vessel maturation and tissue regeneration. Biomaterials which can promote M2 polarisation after appropriate inflam...

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Bibliographic Details
Main Authors: CL Yang, YH Sun, WH Yu, XZ Yin, J Weng, B Feng
Format: Article
Language:English
Published: AO Research Institute Davos 2018-07-01
Series:European Cells & Materials
Subjects:
Genipin cross-linked gelatine
interleukin-4
controlled release
macrophage phenotype polarisation
inflammatory reaction.
Online Access:http://www.ecmjournal.org/papers/vol036/pdf/v036a02.pdf

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