Leishmania (Viannia) braziliensis Inositol Phosphorylceramide: Distinctive Sphingoid Base Composition

Leishmania (Viannia) braziliensis Inositol Phosphorylceramide: Distinctive Sphingoid Base Composition

Inositol phosphorylceramide (IPC), the major sphingolipid in the genus Leishmania but not found in mammals, is considered a potentially useful target for chemotherapy against leishmaniasis. Leishmania (Viannia) braziliensis is endemic in Latin America and causes American tegumentary leishmaniasis. W...

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Bibliographic Details
Main Authors: Erica V. De Castro Levatti, Marcos S. Toledo, Renata Watanabe Costa, Diana Bahia, Renato A. Mortara, Helio K. Takahashi, Anita H. Straus
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-08-01
Series:Frontiers in Microbiology
Subjects:
antibody
ceramide
phosphoinositide
mass spectrometry
sphingolipid
eicosasphinganine
Online Access:http://journal.frontiersin.org/article/10.3389/fmicb.2017.01453/full

Internet

http://journal.frontiersin.org/article/10.3389/fmicb.2017.01453/full

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