A modular synthesis of tetracyclic meroterpenoid antibiotics

A modular synthesis of tetracyclic meroterpenoid antibiotics

Polycyclic meroterpenoids show a wide range of biological activities. Here, the authors report a modular approach to synthesize a number of natural and non-natural tetracyclic meroterpenoids, which display antibiotic activity against methicillin-resistant Staphylococcus aureus.

Bibliographic Details
Main Authors: Raphael Wildermuth, Klaus Speck, Franz-Lucas Haut, Peter Mayer, Bianka Karge, Mark Brönstrup, Thomas Magauer
Format: Article
Language:English
Published: Nature Publishing Group 2017-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-02061-7

Internet

https://doi.org/10.1038/s41467-017-02061-7

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