ROS-dependent HIF1α activation under forced lipid catabolism entails glycolysis and mitophagy as mediators of higher proliferation rate in cervical cancer cells

Abstract Background In the last decades, the concept of metabolic rewiring as a cancer hallmark has been expanded beyond the “Warburg effect” and the importance of other metabolic routes, including lipid metabolism, has emerged. In cancer, lipids are not only a source of energy but are also required...

Full description

Bibliographic Details
Main Authors: Serena Castelli, Fabio Ciccarone, Daniela Tavian, Maria Rosa Ciriolo
Format: Article
Language:English
Published: BMC 2021-03-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
ROS
Online Access:https://doi.org/10.1186/s13046-021-01887-w

Similar Items