Mechanisms of EGF Regulation of COX-2 Through the STAT5 Signaling Pathway 
in Human Lung Adenocarcinoma A549 Cells

Mechanisms of EGF Regulation of COX-2 Through the STAT5 Signaling Pathway 
in Human Lung Adenocarcinoma A549 Cells

Background and objective It has been proved that cyclooxygenase-2 (COX-2) is a key factor in lung cancer oncogenesis. COX-2 can be induced by a number of cytokines and growth factors and can be regulated by the JAK/STAT signaling pathway. Inhibiting the expression of COX-2 can prevent the developmen...

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Bibliographic Details
Main Authors: Jian CUI, Yubo YAN, Yanzhong XIN, Jiyao LI, Qing DONG, Guibin ZHAO, Jingquan HAN, Shouqiang CAO
Format: Article
Language:zho
Published: Chinese Anti-Cancer Association; Chinese Antituberculosis Association 2013-04-01
Series:Chinese Journal of Lung Cancer
Subjects:
STAT5
COX-2
Lung neoplasms
A549
EGF
Online Access:http://dx.doi.org/10.3779/j.issn.1009-3419.2013.04.01

Internet

http://dx.doi.org/10.3779/j.issn.1009-3419.2013.04.01

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