Focal and Reentrant Mechanisms of Torsades de Pointes: EAD, Reentry, or Chimera?

Focal and Reentrant Mechanisms of Torsades de Pointes: EAD, Reentry, or Chimera?

Torsades de pointes (TdP. is characterized not only by its electrocardiographic morphology but also by a tendency to spontaneously terminate. Although clinical and experimental studies suggested that TdP is triggered exclusively by early afterdepolarization, the reentrant mechanism seems to play a c...

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Main Author: Yuji Murakawa, MD
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Journal of Arrhythmia
Subjects:
Purkinje network
Cesium
Anthopleurin-A
Polymorphic ventricular tachyarrhythmias
Spiral wave
Online Access:http://www.sciencedirect.com/science/article/pii/S1880427611800050
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spelling doaj-826f10af0e8544b9b859336c168bb2422020-11-25T00:28:33ZengWileyJournal of Arrhythmia1880-42762011-01-01271283710.1016/S1880-4276(11)80005-0Focal and Reentrant Mechanisms of Torsades de Pointes: EAD, Reentry, or Chimera?Yuji Murakawa, MDTorsades de pointes (TdP. is characterized not only by its electrocardiographic morphology but also by a tendency to spontaneously terminate. Although clinical and experimental studies suggested that TdP is triggered exclusively by early afterdepolarization, the reentrant mechanism seems to play a certain role in its maintenance. In this article, I review the studies that investigated the origin and activation sequences of the twisting QRS complexes of TdP, and discuss whether it is fortunate or unfortunate for us if TdP has something to do with reentry.http://www.sciencedirect.com/science/article/pii/S1880427611800050Purkinje networkCesiumAnthopleurin-APolymorphic ventricular tachyarrhythmiasSpiral wave
collection DOAJ
language English
format Article
sources DOAJ
author Yuji Murakawa, MD
spellingShingle Yuji Murakawa, MD
Focal and Reentrant Mechanisms of Torsades de Pointes: EAD, Reentry, or Chimera?
Journal of Arrhythmia
Purkinje network
Cesium
Anthopleurin-A
Polymorphic ventricular tachyarrhythmias
Spiral wave
author_facet Yuji Murakawa, MD
author_sort Yuji Murakawa, MD
title Focal and Reentrant Mechanisms of Torsades de Pointes: EAD, Reentry, or Chimera?
title_short Focal and Reentrant Mechanisms of Torsades de Pointes: EAD, Reentry, or Chimera?
title_full Focal and Reentrant Mechanisms of Torsades de Pointes: EAD, Reentry, or Chimera?
title_fullStr Focal and Reentrant Mechanisms of Torsades de Pointes: EAD, Reentry, or Chimera?
title_full_unstemmed Focal and Reentrant Mechanisms of Torsades de Pointes: EAD, Reentry, or Chimera?
title_sort focal and reentrant mechanisms of torsades de pointes: ead, reentry, or chimera?
publisher Wiley
series Journal of Arrhythmia
issn 1880-4276
publishDate 2011-01-01
description Torsades de pointes (TdP. is characterized not only by its electrocardiographic morphology but also by a tendency to spontaneously terminate. Although clinical and experimental studies suggested that TdP is triggered exclusively by early afterdepolarization, the reentrant mechanism seems to play a certain role in its maintenance. In this article, I review the studies that investigated the origin and activation sequences of the twisting QRS complexes of TdP, and discuss whether it is fortunate or unfortunate for us if TdP has something to do with reentry.
topic Purkinje network
Cesium
Anthopleurin-A
Polymorphic ventricular tachyarrhythmias
Spiral wave
url http://www.sciencedirect.com/science/article/pii/S1880427611800050
work_keys_str_mv AT yujimurakawamd focalandreentrantmechanismsoftorsadesdepointeseadreentryorchimera
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