Corneal higher order aberrations after intrastromal corneal ring segment implantation for keratoconus

Background Keratoconus is the most common primary corneal ectatic disease. It is a progressive, noninflammatory, and localized paraxial stromal thinning of the cornea, which often results in bilateral and asymmetrical corneal distortion and anterior corneal protrusion. Patients with corneal protrusi...

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Main Authors: Mohamed Y.S Saif, Mostafa A Saeed, Mohamed A Mekky
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2020-01-01
Series:Delta Journal of Ophthalmology
Subjects:
Online Access:http://www.djo.eg.net/article.asp?issn=1110-9173;year=2020;volume=21;issue=1;spage=19;epage=24;aulast=Saif
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spelling doaj-8262b03e1b2e412b82f18f425aad3a7a2021-10-06T13:47:07ZengWolters Kluwer Medknow PublicationsDelta Journal of Ophthalmology1110-91732090-48352020-01-01211192410.4103/DJO.DJO_35_19Corneal higher order aberrations after intrastromal corneal ring segment implantation for keratoconusMohamed Y.S SaifMostafa A SaeedMohamed A MekkyBackground Keratoconus is the most common primary corneal ectatic disease. It is a progressive, noninflammatory, and localized paraxial stromal thinning of the cornea, which often results in bilateral and asymmetrical corneal distortion and anterior corneal protrusion. Patients with corneal protrusion often develop high myopia and irregular astigmatism, resulting in significant impairment of visual acuity. Purpose The aim of this study was to assess changes of higher order aberrations (HOAs) induced by the implantation of intrastromal corneal ring segments (ICRS) in keratoconus. Patients and methods In the current study, a prospective analysis of HOAs, measured by using Pentacam, before and after ICRS implantation was done in a nonrandomized consecutive series of 20 eyes having progressive grade II/III keratoconus (Amsler-Krumeich classification). Results At 1 month postoperatively, a statistically highly significant reduction was found in keratometric readings. The flattest keratometric reading (K1) improved from 46.42±3.08 D preoperatively to 43.25±3.45 D postoperatively, which is highly significant (P<0.01). The steepest keratometric reading (K2) improved from 49.96±3.29 D preoperatively to 46.04±3.15 D postoperatively, which is highly significant (P>0.01). The total HOA root mean square improved from 1.55±0.54 preoperatively to 1.26±0.38 postoperatively, with a statistically significant difference (P<0.05). Primary coma improved from 1.27±0.54 preoperatively to 0.87±0.27 postoperatively, which is highly significant (P>0.01). In addition, astigmatism root mean square changed from 2.42±1.52 preoperatively to 1.98±1.31 postoperatively. Trifoil and quadrifoil showed nonsignificant changes (P>0.05). Conclusion ICRS (Keraring) implantation using femtosecond laser is an effective method for improvement and stabilization of optical, keratometric, and aberrometric measures in keratoconic eyes. Most of the improvement in HOAs was achieved after 1 month and nearly locked up or changed insignificantly till the third month.http://www.djo.eg.net/article.asp?issn=1110-9173;year=2020;volume=21;issue=1;spage=19;epage=24;aulast=Saifhigher order aberrationsintrastromal corneal ring segment implantationkeratoconuspentacam
collection DOAJ
language English
format Article
sources DOAJ
author Mohamed Y.S Saif
Mostafa A Saeed
Mohamed A Mekky
spellingShingle Mohamed Y.S Saif
Mostafa A Saeed
Mohamed A Mekky
Corneal higher order aberrations after intrastromal corneal ring segment implantation for keratoconus
Delta Journal of Ophthalmology
higher order aberrations
intrastromal corneal ring segment implantation
keratoconus
pentacam
author_facet Mohamed Y.S Saif
Mostafa A Saeed
Mohamed A Mekky
author_sort Mohamed Y.S Saif
title Corneal higher order aberrations after intrastromal corneal ring segment implantation for keratoconus
title_short Corneal higher order aberrations after intrastromal corneal ring segment implantation for keratoconus
title_full Corneal higher order aberrations after intrastromal corneal ring segment implantation for keratoconus
title_fullStr Corneal higher order aberrations after intrastromal corneal ring segment implantation for keratoconus
title_full_unstemmed Corneal higher order aberrations after intrastromal corneal ring segment implantation for keratoconus
title_sort corneal higher order aberrations after intrastromal corneal ring segment implantation for keratoconus
publisher Wolters Kluwer Medknow Publications
series Delta Journal of Ophthalmology
issn 1110-9173
2090-4835
publishDate 2020-01-01
description Background Keratoconus is the most common primary corneal ectatic disease. It is a progressive, noninflammatory, and localized paraxial stromal thinning of the cornea, which often results in bilateral and asymmetrical corneal distortion and anterior corneal protrusion. Patients with corneal protrusion often develop high myopia and irregular astigmatism, resulting in significant impairment of visual acuity. Purpose The aim of this study was to assess changes of higher order aberrations (HOAs) induced by the implantation of intrastromal corneal ring segments (ICRS) in keratoconus. Patients and methods In the current study, a prospective analysis of HOAs, measured by using Pentacam, before and after ICRS implantation was done in a nonrandomized consecutive series of 20 eyes having progressive grade II/III keratoconus (Amsler-Krumeich classification). Results At 1 month postoperatively, a statistically highly significant reduction was found in keratometric readings. The flattest keratometric reading (K1) improved from 46.42±3.08 D preoperatively to 43.25±3.45 D postoperatively, which is highly significant (P<0.01). The steepest keratometric reading (K2) improved from 49.96±3.29 D preoperatively to 46.04±3.15 D postoperatively, which is highly significant (P>0.01). The total HOA root mean square improved from 1.55±0.54 preoperatively to 1.26±0.38 postoperatively, with a statistically significant difference (P<0.05). Primary coma improved from 1.27±0.54 preoperatively to 0.87±0.27 postoperatively, which is highly significant (P>0.01). In addition, astigmatism root mean square changed from 2.42±1.52 preoperatively to 1.98±1.31 postoperatively. Trifoil and quadrifoil showed nonsignificant changes (P>0.05). Conclusion ICRS (Keraring) implantation using femtosecond laser is an effective method for improvement and stabilization of optical, keratometric, and aberrometric measures in keratoconic eyes. Most of the improvement in HOAs was achieved after 1 month and nearly locked up or changed insignificantly till the third month.
topic higher order aberrations
intrastromal corneal ring segment implantation
keratoconus
pentacam
url http://www.djo.eg.net/article.asp?issn=1110-9173;year=2020;volume=21;issue=1;spage=19;epage=24;aulast=Saif
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