Distinct neuropeptide-receptor modules regulate a sex-specific behavioral response to a pheromone

Reilly et al identify a neuropeptide-neuropeptide receptor (NP/NPR) module that is active in male but not in hermaphrodite C. elegans. Using a neuropeptide rescue paradigm, they demonstrate that receptor expression within pre-motor neurons mediates coordination of male-specific and core locomotor ci...

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Bibliographic Details
Main Authors: Douglas K. Reilly, Emily J. McGlame, Elke Vandewyer, Annalise N. Robidoux, Caroline S. Muirhead, Haylea T. Northcott, William Joyce, Mark J. Alkema, Robert J. Gegear, Isabel Beets, Jagan Srinivasan
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-02547-7
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Summary:Reilly et al identify a neuropeptide-neuropeptide receptor (NP/NPR) module that is active in male but not in hermaphrodite C. elegans. Using a neuropeptide rescue paradigm, they demonstrate that receptor expression within pre-motor neurons mediates coordination of male-specific and core locomotor circuitries.
ISSN:2399-3642