Structural identification of N-glycan isomers using logically derived sequence tandem mass spectrometry

Structural identification of N-glycan isomers using logically derived sequence tandem mass spectrometry

Mass spectrometry can be used for structural determination of N-glycans, but commonly requires prior derivatisation or comparison to a library of standards. Here logically-derived sequence tandem mass spectrometry allows for assignment of native N-glycans by analysis of successive fragmentation patt...

Full description

Bibliographic Details
Main Authors: Chia Yen Liew, Chu-Chun Yen, Jien-Lian Chen, Shang-Ting Tsai, Sujeet Pawar, Chung-Yi Wu, Chi-Kung Ni
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Communications Chemistry
Online Access:https://doi.org/10.1038/s42004-021-00532-z
Description
Summary:Mass spectrometry can be used for structural determination of N-glycans, but commonly requires prior derivatisation or comparison to a library of standards. Here logically-derived sequence tandem mass spectrometry allows for assignment of native N-glycans by analysis of successive fragmentation patterns without derivatisation and standards.
ISSN:2399-3669

Similar Items