High loading of trimethylglycine promotes aqueous solubility of poorly water-soluble cisplatin

Abstract Trimethylglycine (TMG) is a cheap, natural, and highly biocompatible compound. Therefore, it has been used in the fields of food and life sciences, but the application of solid TMG is limited to utilisation as an “additive”. In the present study, we focussed on the high solubility of TMG in...

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Bibliographic Details
Main Authors: Riki Kadokawa, Tetsuo Fujie, Gyanendra Sharma, Kojiro Ishibashi, Kazuaki Ninomiya, Kenji Takahashi, Eishu Hirata, Kosuke Kuroda
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-89144-0