The Warburg Effect Is Associated With Tumor Aggressiveness in Testicular Germ Cell Tumors

The Warburg Effect Is Associated With Tumor Aggressiveness in Testicular Germ Cell Tumors

Testicular Germ Cell Tumors (TGCTs) are a rare group of neoplasms and the most common solid malignancy arising in young male adults. Despite the good response of these tumors to platinum-based chemotherapy, some patients are refractory to treatment and present poor clinical outcomes. During carcinog...

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Bibliographic Details
Main Authors: Murilo Bonatelli, Eduardo C. A. Silva, Flavio M. Cárcano, Maurício G. Zaia, Luiz F. Lopes, Cristovam Scapulatempo-Neto, Céline Pinheiro
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Endocrinology
Subjects:
immunohistochemistry
metabolic reprogramming
testicular germ cell tumors
testicular neoplasms
Warburg effect
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2019.00417/full

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