Longitudinal stability in cigarette smokers of urinary eicosanoid biomarkers of oxidative damage and inflammation.

Longitudinal stability in cigarette smokers of urinary eicosanoid biomarkers of oxidative damage and inflammation.

The urinary metabolites (Z)-7-[1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]cyclopentyl]hept-5-enoic acid (8-iso-PGF2α), an F2-isoprostane and biomarker of oxidative damage, and "prostaglandin E2 metabolite" (PGE-M), a biomarker of inflammation, are elevated in cigarette smoker...

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Bibliographic Details
Main Authors: Steven G Carmella, Alisa K Heskin, Mei Kuen Tang, Joni Jensen, Xianghua Luo, Chap T Le, Sharon E Murphy, Neal L Benowitz, F Joseph McClernon, Ryan Vandrey, Sharon S Allen, Rachel Denlinger-Apte, Paul M Cinciripini, Andrew A Strasser, Mustafa al'Absi, Jason D Robinson, Eric C Donny, Dorothy K Hatsukami, Stephen S Hecht
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0215853

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