Anticancer and apoptosis-inducing effects of Moringa concanensis using hepG2 cell lines

Anticancer and apoptosis-inducing effects of Moringa concanensis using hepG2 cell lines

Show other versions (1)

The objective of the present investigation is focused on the anticancer activity of the ethanolic crude extract of Moringa concanensis leaf and bark against HepG2 cell line. The study was facilitated by collecting the plant sample and subjected to ethanol crude extraction. The anticancer activity o...

Full description

Bibliographic Details
Main Authors: V. Balamurugan, Veluchamy Balakrishnan, J. Philip Robinson, M. Ramakrishnan
Format: Article
Language:English
Published: Bangladesh Pharmacological Society 2014-11-01
Series:Bangladesh Journal of Pharmacology
Subjects:
Anti-cancer
HepG-2 cell line
Moringa concanensis
MTT assay
Online Access:https://www.banglajol.info/index.php/BJP/article/view/20481
id doaj-823a36e715a3420aabcbb52aab4868bb
record_format Article
spelling doaj-823a36e715a3420aabcbb52aab4868bb2020-11-25T00:34:18ZengBangladesh Pharmacological SocietyBangladesh Journal of Pharmacology1991-00882014-11-0194Anticancer and apoptosis-inducing effects of Moringa concanensis using hepG2 cell linesV. Balamurugan0Veluchamy Balakrishnan1J. Philip Robinson2M. Ramakrishnan3Research and Development Centre, Bharathiar University, Coimbatore 641 046, Tamil NaduResearch and Development Centre, Bharathiar University, Coimbatore 641 046, Tamil NaduDepartment of Biotechnology, K. S. Rangasamy College of Technology (Autonomous), Tiruchengode 637 215, Tamil NaduDepartment of Biotechnology, Sri Vinayaga College of Arts and Science, Ulundurpet 606 107, Tamil Nadu The objective of the present investigation is focused on the anticancer activity of the ethanolic crude extract of Moringa concanensis leaf and bark against HepG2 cell line. The study was facilitated by collecting the plant sample and subjected to ethanol crude extraction. The anticancer activity of the crude extracted sample against HepG2 cell line was examined by MTT assay. The study confirms that the leaf crude extract of M. concanensis has pronounced anticancer potential against HepG2 cell lines while compared to that of the bark extract. The plant investigated possesses remarkable anticancer activity and hence isolation of the compound contributing to the activity may lead to develop at a novel and natural phytomedicine for the disease. https://www.banglajol.info/index.php/BJP/article/view/20481Anti-cancerHepG-2 cell lineMoringa concanensisMTT assay
collection DOAJ
language English
format Article
sources DOAJ
author V. Balamurugan
Veluchamy Balakrishnan
J. Philip Robinson
M. Ramakrishnan
spellingShingle V. Balamurugan
Veluchamy Balakrishnan
J. Philip Robinson
M. Ramakrishnan
Anticancer and apoptosis-inducing effects of Moringa concanensis using hepG2 cell lines
Bangladesh Journal of Pharmacology
Anti-cancer
HepG-2 cell line
Moringa concanensis
MTT assay
author_facet V. Balamurugan
Veluchamy Balakrishnan
J. Philip Robinson
M. Ramakrishnan
author_sort V. Balamurugan
title Anticancer and apoptosis-inducing effects of Moringa concanensis using hepG2 cell lines
title_short Anticancer and apoptosis-inducing effects of Moringa concanensis using hepG2 cell lines
title_full Anticancer and apoptosis-inducing effects of Moringa concanensis using hepG2 cell lines
title_fullStr Anticancer and apoptosis-inducing effects of Moringa concanensis using hepG2 cell lines
title_full_unstemmed Anticancer and apoptosis-inducing effects of Moringa concanensis using hepG2 cell lines
title_sort anticancer and apoptosis-inducing effects of moringa concanensis using hepg2 cell lines
publisher Bangladesh Pharmacological Society
series Bangladesh Journal of Pharmacology
issn 1991-0088
publishDate 2014-11-01
description The objective of the present investigation is focused on the anticancer activity of the ethanolic crude extract of Moringa concanensis leaf and bark against HepG2 cell line. The study was facilitated by collecting the plant sample and subjected to ethanol crude extraction. The anticancer activity of the crude extracted sample against HepG2 cell line was examined by MTT assay. The study confirms that the leaf crude extract of M. concanensis has pronounced anticancer potential against HepG2 cell lines while compared to that of the bark extract. The plant investigated possesses remarkable anticancer activity and hence isolation of the compound contributing to the activity may lead to develop at a novel and natural phytomedicine for the disease.
topic Anti-cancer
HepG-2 cell line
Moringa concanensis
MTT assay
url https://www.banglajol.info/index.php/BJP/article/view/20481
work_keys_str_mv AT vbalamurugan anticancerandapoptosisinducingeffectsofmoringaconcanensisusinghepg2celllines
AT veluchamybalakrishnan anticancerandapoptosisinducingeffectsofmoringaconcanensisusinghepg2celllines
AT jphiliprobinson anticancerandapoptosisinducingeffectsofmoringaconcanensisusinghepg2celllines
AT mramakrishnan anticancerandapoptosisinducingeffectsofmoringaconcanensisusinghepg2celllines
_version_ 1725314208000638976

Similar Items