| Summary: | Objective Aim of this study was to evaluate the short term effect of coffee drinking on energy utilization in sedentary men. Methods This study was performed in healthy sedentary men, who were randomized into three groups, control (n = 6), decaffeinated (n = 10), and caffeine (n = 10). The caffeine dose in coffee was rechecked and calculated for individual volunteers at 5 mg/kg. Baseline before drinking, complete blood count (CBC), glucose, antioxidant capacity, lipid peroxide, and caffeine in blood was evaluated. After drinking coffee for 1 hr, the submaximal exercise test with a modified Bruce protocol was carried out, and the VO 2 and RER were analyzed individually at 80% maximal heart rate, then the blood was repeat evaluated. Results Three groups showed a nonsignificant difference in CBC results and physical characteristics. The caffeine group showed significant changes in all parameters; higher VO 2 levels, ( P = 0.037) and lower RER ( P = 0.047), when compared to the baseline. Furthermore, the glucose level after exercise test increased significantly ( P = 0.033) as well as lipid peroxide levels ( P = 0.005), whereas antioxidant capacity did not change significantly ( P = 0.759), when compared to the before exercise testing. In addition, the blood caffeine level also increased only in the caffeine group ( P = 0.008). Conclusion Short consumption of caffeinated coffee (5 mg/kg of caffeine), improves energy utilization and relates to glucose derivation and lipid oxidation.
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