Cytological Features of Parachordoma: Two Case Reports of a Rare Entity

• Main Authors: Neelam Sood, Kumar Sharad Sinha
• Format: Article
• Language: English
• Published: Krishna Institute of Medical Sciences University 2016-04-01
• Series: Journal of Krishna Institute of Medical Sciences University
• Subjects: Cytology; Recurrent; Parachordoma; Physaliphorous
• Online Access: http://www.jkimsu.com/jkimsu-vol5no2/JKIMSU,%20Vol.%205,%20No.%202,%20April-June%202016%20Page%20140-144.pdf

Parachordoma is an uncommon tumour of soft tissue of uncertain origin. Recurrence and metastasis are rarely seen. We report two cases with one presenting as recurrent case of pelvic parachordoma in a 45 year old female who presented with painless pelvic mass since 2 months. The other case report is of a 30 year male patient who presented with a diffuse swelling over left palmar aspect. Cytology findings of the pelvic swelling revealed moderately cellular smears composed of large physaliphorous cells with abundant bubbly cytoplasm in clusters and singly scattered medium sized epithelioid like cells with round nuclei, vesicular chromatin and prominent nucleoli in background of abundant myxoid ground substance. Cytology of the Palmar swelling revealed moderate cellularity comprised of oval to spindle shaped cells with coarse chromatin, prominent nucleoli and abundant vacuolated cytoplasm in a chondomyxoid stromal background. The preliminary diagnosis on cytology with further confirmation on histopathology with the aid of immunohistochemistry helped clinch the diagnosis of this rare entity of parachordoma occurring at unusual sites.