Overexpression of biotin synthase and biotin ligase is required for efficient generation of sulfur-35 labeled biotin in <it>E. coli</it>

<p>Abstract</p> <p>Background</p> <p>Biotin is an essential enzyme cofactor that acts as a CO<sub>2 </sub>carrier in carboxylation and decarboxylation reactions. The <it>E. coli </it>genome encodes a biosynthetic pathway that produces biotin from...

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Bibliographic Details
Main Authors: Prigge Sean T, Spalding Maroya D, Delli-Bovi Teegan A
Format: Article
Language:English
Published: BMC 2010-10-01
Series:BMC Biotechnology
Online Access:http://www.biomedcentral.com/1472-6750/10/73

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