Tumor Budding, Micropapillary Pattern, and Polyploidy Giant Cancer Cells in Colorectal Cancer: Current Status and Future Prospects

Tumor Budding, Micropapillary Pattern, and Polyploidy Giant Cancer Cells in Colorectal Cancer: Current Status and Future Prospects

We previously reported that polyploid giant cancer cells (PGCGs) induced by CoCl2 could form through endoreduplication or cell fusion. A single PGCC formed tumors in immunodeficient mice. PGCCs are also the key contributors to the cellular atypia and associate with the malignant grade of tumors. PGC...

Full description

Bibliographic Details
Main Authors:	Shiwu Zhang, Dan Zhang, Zhengduo Yang, Xipeng Zhang
Format:	Article
Language:	English
Published:	Hindawi Limited 2016-01-01
Series:	Stem Cells International
Online Access:	http://dx.doi.org/10.1155/2016/4810734

Similar Items

Biomarkers in Colorectal Cancer: Current Research and Future Prospects
by: Olorunseun O. Ogunwobi, et al.
Published: (2020-07-01)

iTRAQ-based proteomic analysis of polyploid giant cancer cells and budding progeny cells reveals several distinct pathways for ovarian cancer development.
by: Shiwu Zhang, et al.
Published: (2013-01-01)

Refractory Metastatic Colorectal Cancer: Current Challenges and Future Prospects
by: Lam M, et al.
Published: (2020-07-01)

Asymmetric Cell Division in Polyploid Giant Cancer Cells and Low Eukaryotic Cells
by: Dan Zhang, et al.
Published: (2014-01-01)

Number of Polyploid Giant Cancer Cells and Expression of EZH2 Are Associated with VM Formation and Tumor Grade in Human Ovarian Tumor
by: Li Zhang, et al.
Published: (2014-01-01)

Computer-Aided Diagnosis in Colorectal Cancer: Current Concepts and Future Prospects
by: Ioanovici Andrei-Constantin, et al.
Published: (2017-09-01)

Current status and future prospects of PARP inhibitor clinical trials in ovarian cancer
by: Jiang X, et al.
Published: (2019-05-01)

The role of mSEPT9 in screening, diagnosis, and recurrence monitoring of colorectal cancer
by: Jie Sun, et al.
Published: (2019-05-01)

Current Status of Immunotherapy for Metastatic Colorectal Cancer
by: LIU Zhaohui, et al.
Published: (2020-12-01)

Micropapillary bladder cancer: A clinicopathologic characterization and treatment analysis
by: A. Saadi, et al.
Published: (2020-11-01)

Micropapillary bladder cancer: a review of Léon Bérard Cancer Center experience
by: Droz Jean-Pierre, et al.
Published: (2009-06-01)

Micropapillary Pattern at the Invasive Front and Its Association with Unresectable Colorectal Carcinomas
by: Naohiko Akimoto, et al.
Published: (2013-01-01)

Molecular Diagnostics for Precision Medicine in Colorectal Cancer: Current Status and Future Perspective
by: Guoli Chen, et al.
Published: (2016-01-01)

Tumor Budding, uPA, and PAI-1 in Colorectal Cancer: Update of a Prospective Study
by: Bruno Märkl, et al.
Published: (2017-01-01)

Pathological and Molecular Features of Lung Micropapillary Adenocarcinoma
by: Jiafeng LIANG, et al.
Published: (2020-11-01)

Future Prospects of Colorectal Cancer Screening: Characterizing Interval Cancers
by: Gemma Ibáñez-Sanz, et al.
Published: (2021-03-01)

RAS, Cellular Plasticity, and Tumor Budding in Colorectal Cancer
by: Valeria Maffeis, et al.
Published: (2019-11-01)

Molecular and pathogenetic aspects of tumor budding in colorectal cancer
by: Heather eDawson, et al.
Published: (2015-03-01)

Induction of Polyploidy in Giant Miscanthus (Miscanthus × Giganteus Greef Et Deu.)
by: Melnychuk Oleksandr V., et al.
Published: (2020-06-01)

Immunotherapy in Colorectal Cancer: Current and Future Strategies
by: Akira Ooki, et al.
Published: (2021-01-01)

Translational Research in Colorectal Cancer: Current Status and Future Perspectives of Multimodal Treatment Approach
by: Luigi Marano, et al.
Published: (2019-01-01)

Micropapillary Variant of Urothelial Carcinoma
by: Ghee Young Kwon, et al.
Published: (2011-01-01)

Micropapillary carcinoma of urinary bladder
by: Shah Vinaya, et al.
Published: (2008-04-01)

Laparoscopic surgery for colorectal cancers: Current status
by: Shukla Parul, et al.
Published: (2006-01-01)

Colon cancer with micropapillary carcinoma component: a clinopathologic study of 9 cases
by: Naoto Kuroda, et al.
Published: (2017-08-01)

Tasquinimod in the treatment of castrate-resistant prostate cancer – current status and future prospects
by: Amit R. Mehta, et al.
Published: (2016-02-01)

Prognostic Significance of a Micropapillary Pattern in Pure Mucinous Carcinoma of the Breast: Comparative Analysis with Micropapillary Carcinoma
by: Hyun-Jung Kim, et al.
Published: (2017-07-01)

Interventional Radiology in China: Current Status and Future Prospects
by: He Zhao, et al.
Published: (2017-01-01)

Formation of Polyploid Giant Cancer Cells Involves in the Prognostic Value of Neoadjuvant Chemoradiation in Locally Advanced Rectal Cancer
by: Fei Fei, et al.
Published: (2019-01-01)

Colorectal cancer screening in middle eastern countries: Current status and future strategies to enhance screening
by: Martin C. S. Wong, et al.
Published: (2019-01-01)

Serrated polyps as precursor lesions of colorectal cancer: current status and future directions. Mini-review.
by: І. О. Kuzo
Published: (2016-08-01)

Tumour budding, poorly differentiated clusters, and T-cell response in colorectal cancer
by: Kenji Fujiyoshi, et al.
Published: (2020-07-01)

The sonographic findings of micropapillary pattern in pure mucinous carcinoma of the breast
by: Heqing Zhang, et al.
Published: (2018-07-01)

Invasive Micropapillary Carcinoma of the Uterine Cervix
by: Hyun Hee Koh, et al.
Published: (2020-12-01)

Micropapillary Carcinoma of the Bladder: Recent Advances
by: Jim Hsu, et al.
Published: (2019-07-01)

Advances of Pulmonary Adenocarcinoma with Micropapillary Pattern
by: Xiangyu SHI, et al.
Published: (2015-11-01)

Nanoparticle Delivery of Natural Products in the Prevention and Treatment of Cancers: Current Status and Future Prospects
by: Hasan Mukhtar, et al.
Published: (2011-10-01)

Pneumoconiosis: current status and future prospects
by: Xian-Mei Qi, et al.
Published: (2021-04-01)

Immune Checkpoint Inhibitors in Colorectal Cancer: Challenges and Future Prospects
by: Shima Makaremi, et al.
Published: (2021-08-01)

Cell Budding from Normal Appearing Epithelia: A Predictor of Colorectal Cancer Metastasis?
by: Bin Jiang, Jeffrey Mason, Anahid Jewett, Jun Qian, Yijiang Ding, William CS Cho, Xichen Zhang, Yan-gao Man
Published: (2013-01-01)