Influence of type I IFN signaling on anti-MOG antibody-mediated demyelination

Influence of type I IFN signaling on anti-MOG antibody-mediated demyelination

Abstract Background Antibodies with specificity for myelin oligodendrocyte glycoprotein (MOG) are implicated in multiple sclerosis and related diseases. The pathogenic importance of anti-MOG antibody in primary demyelinating pathology remains poorly characterized. Objective The objective of this stu...

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Bibliographic Details
Main Authors: Carsten Tue Berg, Reza Khorooshi, Nasrin Asgari, Trevor Owens
Format: Article
Language:English
Published: BMC 2017-06-01
Series:Journal of Neuroinflammation
Subjects:
Beta-interferon
Demyelination
Histopathology
Immunology
Animal model
Experimental autoimmune encephalomyelitis
Online Access:http://link.springer.com/article/10.1186/s12974-017-0899-1

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http://link.springer.com/article/10.1186/s12974-017-0899-1

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