Defining the ligand specificity of the deleted in colorectal cancer (DCC) receptor.

The growth and guidance of many axons in the developing nervous system require Netrin-mediated activation of Deleted in Colorectal Cancer (DCC) and other still unknown signaling cues. Commissural axon guidance defects are more severe in DCC mutant mice than Netrin-1 mutant mice, suggesting additiona...

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Bibliographic Details
Main Authors: Patrick C G Haddick, Irene Tom, Elizabeth Luis, Gabriel Quiñones, Bernd J Wranik, Sree R Ramani, Jean-Philippe Stephan, Marc Tessier-Lavigne, Lino C Gonzalez
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3882260?pdf=render