Vitamin B6 deficiency hyperactivates the noradrenergic system, leading to social deficits and cognitive impairment
Abstract We have reported that a subpopulation of patients with schizophrenia have lower levels of vitamin B6 (VB6) in peripheral blood than do healthy controls. In a previous study, we found that VB6 level was inversely proportional to the patient’s positive and negative symptom scale (PANSS) score...
Main Authors: | Kazuya Toriumi, Mitsuhiro Miyashita, Kazuhiro Suzuki, Nao Yamasaki, Misako Yasumura, Yasue Horiuchi, Akane Yoshikawa, Mai Asakura, Noriyoshi Usui, Masanari Itokawa, Makoto Arai |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-05-01
|
Series: | Translational Psychiatry |
Online Access: | https://doi.org/10.1038/s41398-021-01381-z |
Similar Items
-
Dysregulation of post-transcriptional modification by copy number variable microRNAs in schizophrenia with enhanced glycation stress
by: Akane Yoshikawa, et al.
Published: (2021-05-01) -
Combined glyoxalase 1 dysfunction and vitamin B6 deficiency in a schizophrenia model system causes mitochondrial dysfunction in the prefrontal cortex
by: Kazuya Toriumi, et al.
Published: (2021-09-01) -
Advanced glycation end products and cognitive impairment in schizophrenia.
by: Akiko Kobori, et al.
Published: (2021-01-01) -
Fingertip advanced glycation end products and psychotic symptoms among adolescents
by: Mitsuhiro Miyashita, et al.
Published: (2021-08-01) -
Paradox of schizophrenia genetics: is a paradigm shift occurring?
by: Doi Nagafumi, et al.
Published: (2012-05-01)