Thyroid Hormone Receptor Is Essential for Larval Epithelial Apoptosis and Adult Epithelial Stem Cell Development but not Adult Intestinal Morphogenesis during <i>Xenopus tropicalis</i> Metamorphosis

Thyroid Hormone Receptor Is Essential for Larval Epithelial Apoptosis and Adult Epithelial Stem Cell Development but not Adult Intestinal Morphogenesis during <i>Xenopus tropicalis</i> Metamorphosis

Vertebrate postembryonic development is regulated by thyroid hormone (T3). Of particular interest is anuran metamorphosis, which offers several unique advantages for studying the role of T3 and its two nuclear receptor genes, <i>TR</i>α and <i>TRβ</i>, during postembryonic de...

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Bibliographic Details
Main Authors: Yuki Shibata, Yuta Tanizaki, Hongen Zhang, Hangnoh Lee, Mary Dasso, Yun-Bo Shi
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Cells
Subjects:
<i>Xenopus</i> <i>tropicalis</i>
thyroid hormone receptor
transcriptional regulation
amphibian metamorphosis
intestinal remodeling
apoptosis
Online Access:https://www.mdpi.com/2073-4409/10/3/536

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