The master cell cycle regulator APC-Cdc20 regulates ciliary length and disassembly of the primary cilium

The master cell cycle regulator APC-Cdc20 regulates ciliary length and disassembly of the primary cilium

The primary cilium has an important role in signaling; defects in structure are associated with a variety of human diseases. Much of the most basic biology of this organelle is poorly understood, even basic mechanisms, such as control of growth and resorption. We show that the activity of the anapha...

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Bibliographic Details
Main Authors: Weiping Wang, Tao Wu, Marc W Kirschner
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2014-08-01
Series:eLife
Subjects:
primary cilum
ubiquitin
cell cycle
retinal cell culture
Online Access:https://elifesciences.org/articles/03083

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