Low-density lipoprotein receptors play an important role in the inhibition of prostate cancer cell proliferation by statins

Low-density lipoprotein receptors play an important role in the inhibition of prostate cancer cell proliferation by statins

Background: There are some reports about the antitumor effects of statins in these days. Statins decrease the level of cholesterol in the blood by inhibiting 3-hydroxy-3-methylglutaryl-coenzyme A reductase. Inhibition of this enzyme decreases intracellular cholesterol synthesis. Thus, the expression...

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Bibliographic Details
Main Authors: Yosuke Furuya, Yoshitaka Sekine, Haruo Kato, Yoshiyuki Miyazawa, Hidekazu Koike, Kazuhiro Suzuki
Format: Article
Language:English
Published: Elsevier 2016-06-01
Series:Prostate International
Subjects:
Cholesterol
Low-density lipoprotein receptor
Prostate cancer
Statins
Online Access:http://www.sciencedirect.com/science/article/pii/S2287888215301070

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