Afadin controls cell polarization and mitotic spindle orientation in developing cortical radial glia

Afadin controls cell polarization and mitotic spindle orientation in developing cortical radial glia

Abstract Background In developing tissues, cell polarity and tissue architecture play essential roles in the regulation of proliferation and differentiation. During cerebral cortical development, adherens junctions link highly polarized radial glial cells in a neurogenic niche that controls their be...

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Bibliographic Details
Main Authors: Jennifer Rakotomamonjy, Molly Brunner, Christoph Jüschke, Keling Zang, Eric J. Huang, Louis F. Reichardt, Anjen Chenn
Format: Article
Language:English
Published: BMC 2017-05-01
Series:Neural Development
Subjects:
Cortical development
Adherens junctions
Apicobasal polarity
Cell fate
Primary cilia
Online Access:http://link.springer.com/article/10.1186/s13064-017-0085-2

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http://link.springer.com/article/10.1186/s13064-017-0085-2

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