Hypoxia-induced amniotic fluid stem cell secretome augments cardiomyocyte proliferation and enhances cardioprotective effects under hypoxic-ischemic conditions

Hypoxia-induced amniotic fluid stem cell secretome augments cardiomyocyte proliferation and enhances cardioprotective effects under hypoxic-ischemic conditions

Abstract Secretome derived from human amniotic fluid stem cells (AFSC-S) is rich in soluble bioactive factors (SBF) and offers untapped therapeutic potential for regenerative medicine while avoiding putative cell-related complications. Characterization and optimal generation of AFSC-S remains challe...

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Bibliographic Details
Main Authors: Marek Kukumberg, Tatsanee Phermthai, Suparat Wichitwiengrat, Xiaoyuan Wang, Subramanian Arjunan, Suet Yen Chong, Chui-Yee Fong, Jiong-Wei Wang, Abdul Jalil Rufaihah, Citra Nurfarah Zaini Mattar
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-80326-w

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