Extracellular acidosis differentiates pancreatitis and pancreatic cancer in mouse models using acidoCEST MRI

Differentiating pancreatitis from pancreatic cancer would improve diagnostic specificity, and prognosticating pancreatitis that progresses to pancreatic cancer would also improve diagnoses of pancreas pathology. The high glycolytic metabolism of pancreatic cancer can cause tumor acidosis, and differ...

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Bibliographic Details
Main Authors: Rachel A. High, Edward A. Randtke, Kyle M. Jones, Leila R. Lindeman, Jacqueline C. Ma, Shu Zhang, Lucia G. LeRoux, Mark D. Pagel
Format: Article
Language:English
Published: Elsevier 2019-11-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558619301794