1-Methyl-3-{4-[(4-(2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)piperidin-1-yl)benzyl]}-2-phenylindole

1-Methyl-3-{4-[(4-(2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)piperidin-1-yl)benzyl]}-2-phenylindole

The 1-methyl-3-{4-[(4-(2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)piperidin-1-yl)benzyl]}-2-phenylindole compound has been successfully synthesized via a multistep pathway starting from 2-phenylindole. Structure characterization of this new indole derivative was done by FTIR, 1H-NMR, 13C-NMR, and HRMS s...

Full description

Bibliographic Details
Main Authors:	Jean Guillon, Solène Savrimoutou, Sandra Rubio, Vanessa Desplat
Format:	Article
Language:	English
Published:	MDPI AG 2018-10-01
Series:	Molbank
Subjects:	indole derivative leukemia antiproliferative activity
Online Access:	http://www.mdpi.com/1422-8599/2018/4/M1023

Similar Items

1-Phenyl-8-[[4-(pyrrolo[1,2-<i>a</i>]quinoxalin-4-yl)phenyl]methyl]-1,3,8-triazaspiro[4.5]decan-4-one: Synthesis, Crystal Structure and Anti-Leukemic Activity
by: Jean Guillon, et al.
Published: (2020-01-01)

Crystal structure of 3-benzyl-1-[(1,2,3,4-tetrahydronaphthalen-1-ylidene)amino]thiourea
by: Shaaban K. Mohamed, et al.
Published: (2015-12-01)

(E)-2-[4-(Piperidin-1-yl)benzylidene]-2,3-dihydro-1H-inden-1-one
by: Mohamed Ashraf Ali, et al.
Published: (2010-11-01)

3-Oxo-5-(piperidin-1-yl)-2,3-dihydro-1H-pyrazole-4-carbonitrile
by: Wedad M. Al-Adiwish, et al.
Published: (2011-12-01)

4-[4-(Piperidin-1-yl)piperidin-1-yl]benzonitrile
by: Guo-bin Xu, et al.
Published: (2010-02-01)

The crystal structures, Hirshfeld surface analyses and energy frameworks of 8-{1-[3-(cyclopent-1-en-1-yl)benzyl]piperidin-4-yl}-2-methoxyquinoline and 8-{4-[3-(cyclopent-1-en-1-yl)benzyl]piperazin-1-yl}-2-methoxyquinoline
by: Nisar Ullah, et al.
Published: (2021-04-01)

1,3-Bis(1-benzyl-1H-benzimidazol-2-yl)-2-oxapropane
by: Qingyu Sun, et al.
Published: (2009-05-01)

2,6-Bis[(S)-4-benzyl-4,5-dihydro-1,3-oxazol-2-yl]pyridine
by: Konstanze M&#246;ller, et al.
Published: (2011-05-01)

1-(1-Benzyl-1H-benzimidazol-2-yl)ethanone
by: Chuan-Jing Zhang, et al.
Published: (2012-12-01)

Ethyl 2-[1,3-dioxo-6-(piperidin-1-yl)-2,3-dihydro-1H-benz[de]isoquinolin-2-yl]acetate
by: Song Xia, et al.
Published: (2011-07-01)

N-(5-Benzylsulfanyl-1,3,4-thiadiazol-2-yl)-2-(piperidin-1-yl)acetamide
by: D. S. Ismailova, et al.
Published: (2014-03-01)

[2-Benzyl-3-(naphthalen-1-yl)-2,3-dihydro-1,2-oxazole-4,5-diyl]bis(phenylmethanone)
by: R. Sandhya, et al.
Published: (2014-03-01)

2-[1-(3-Oxo-1,3-dihydro-2-benzofuran-1-yl)-1H-benzimidazol-2-yl]benzoic acid methanol solvate
by: Guang Shi, et al.
Published: (2010-08-01)

Dichloridobis[3-(4-methoxyphenyl)-2-methyl-5-(piperidin-1-yl)-2,3-dihydro-1,2,4-oxadiazole-κN4]platinum(II)
by: Valentina A. Kalibabchuk, et al.
Published: (2013-08-01)

(2Z)-2-Benzylidene-4-[(1-benzyl-1H-1,2,3-triazol-4-yl)methyl]-3,4-dihydro-2H-1,4-benzothiazin-3-one
by: Nada Kheira Sebbar, et al.
Published: (2016-11-01)

Nꞌ-{[2-(Piperidin-1-yl)quinolin-3-yl]methylene}pyridine-4-carbohydrazide
by: Rajiv K. Tonk, et al.
Published: (2012-01-01)

3-(1-{[1-(4-Bromophenyl)-1H-1,2,3-triazol-4-yl]methyl}piperidin-4-yl)-6-fluoro-1,2-benzoxazole hemihydrate
by: N. Ashwini, et al.
Published: (2016-01-01)

2,2-Diphenyl-4-(piperidin-1-yl)butanamide
by: M. S. Siddegowda, et al.
Published: (2011-07-01)

3-Benzyl-1-{[3-(4-chlorophenyl)isoxazol-5-yl]methyl}-1H-benzimidazol-2(3H)-one
by: Youssef Kandri Rodi, et al.
Published: (2013-09-01)

2-({4-[4-(1H-Benzimidazol-2-yl)phenyl]-1H-1,2,3-triazol-1-yl}methoxy)ethanol
by: Abdelaaziz Ouahrouch, et al.
Published: (2012-06-01)

Synthesis of 1<i>H</i>-3-{4-[(3-Dimethylaminopropyl)aminomethyl]phenyl}-2-phenylindole and Evaluation of Its Antiprotozoal Activity
by: Jean Guillon, et al.
Published: (2019-05-01)

1,3-Bis[(1H-benzotriazol-1-yl)methyl]-2,3-dihydro-1H-benzimidazole
by: Augusto Rivera, et al.
Published: (2011-04-01)

2-{5-(1,3-Benzodioxol-5-yl)-1-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-4,5-dihydro-1H-pyrazol-3-yl}pyrazine
by: Suban Syed Shafi, et al.
Published: (2010-03-01)

1-Benzyl-2-(thien-2-yl)-4,5-dihydro-1<i>H</i>-imidazole
by: Alexandra S. Golubenkova, et al.
Published: (2020-05-01)

1-{[3-(Thiophen-2-yl)-4,5-dihydro-1,2-oxazol-5-yl]methyl}-2,3-dihydro-1H-indole-2,3-dione
by: Ibtissam Rayni, et al.
Published: (2017-03-01)

Benzyl 2-{[2,8-bis(trifluoromethyl)quinolin-4-yl](hydroxy)methyl}piperidine-1-carboxylate
by: Marcus V. N. de Souza, et al.
Published: (2011-12-01)

N-[4-(4-Bromophenyl)thiazol-2-yl]-4-(piperidin-1-yl)butanamide
by: Hazem A. Ghabbour, et al.
Published: (2012-06-01)

3-Amino-5-(piperidin-1-yl)thiophene-2,4-dicarbonitrile
by: Wedad M. Al-Adiwish, et al.
Published: (2012-01-01)

(S)-1-[(S)-4-Benzyl-2-thioxothiazolidin-3-yl]-3-hydroxybutan-1-one
by: Jian-hong Yang, et al.
Published: (2008-01-01)

2-[4-(Piperidin-1-yl)-5H-chromeno[2,3-d]pyrimidin-2-yl]phenol
by: Naresh Sharma, et al.
Published: (2014-04-01)

Crystal structure of 1-[(2,2-dimethyl-1,3-dioxolan-4-yl)methyl]-2-(thiazol-4-yl)-1H-benzimidazole
by: Hicham Gueddar, et al.
Published: (2015-12-01)

3-[4-(1H-Indol-3-yl)-1,3-thiazol-2-yl]-1H-pyrrolo[2,3-b]pyridines, Nortopsentin Analogues with Antiproliferative Activity
by: Barbara Parrino, et al.
Published: (2015-04-01)

4-[1-(4-Hydroxy-3-methoxybenzyl)-1H-benzimidazol-2-yl]-2-methoxyphenol
by: Zuo-an Xiao, et al.
Published: (2011-11-01)

Synthesis of substituted 2-(1,2,4- triazol-3-yl)benzimidazoles
by: N. V. Ivanova, et al.
Published: (2006-10-01)

6-[2-(4-arylpiperazin-1-yl)ethyl]-4-halo-1,3-dihydro-2h-benzimidazole-2-thiones: Synthesis and pharmacological evaluation
by: Andrić Deana, et al.
Published: (2007-01-01)

6-[2-(4-Arylpiperazin-1-yl)ethyl]-4-halo-1,3-dihydro-2H-benzimidazole-2-thiones: synthesis and pharmacological evaluation
by: DEANA ANDRIC, et al.
Published: (2007-08-01)

2-Chloro-4,6-bis(piperidin-1-yl)-1,3,5-triazine
by: Jasmine P. Vennila, et al.
Published: (2011-02-01)

3-[5-Methyl-1-(4-methylphenyl)-1H-1,2,3-triazol-4-yl]-N-phenyl-5-[4-(piperidin-1-yl)phenyl]-4,5-dihydro-1H-pyrazole-1-carbothioamide dimethylformamide hemisolvate
by: Bakr F. Abdel-Wahab, et al.
Published: (2012-07-01)

1-Benzyl-4-(naphthalen-1-yl)-1H-1,2,3-triazole
by: Juan I. Sarmiento-S&#225;nchez, et al.
Published: (2011-07-01)

1-[(3-Nitrophenyl)(piperidin-1-yl)methyl]piperidine
by: Zhe-Qin Wang, et al.
Published: (2012-06-01)

Cannot write session to /tmp/vufind_sessions/sess_4bs07ccch3i1379c8kl3ltrs49