| Summary: | A technique of alignment and removal of noise is a prominent pre-processing part of biomedical image fusion. The purpose is to evaluate and analyze visually as well as parametric findings. However, considering practical execution still there is need for improvement in pre-processing for image processing applications. Therefore, the problem of blockage and variation in scans of patients, need to be overcome by properly align and denoise input images. Therefore to design the registration algorithm in such a way, it should cover all geometric motions of biomedical images, by which it is useful to the practitioner for the detection of medical defects. Herewith we have proposed a log-polar and phase correlation composite algorithm for the registration of all geometric motions. The proposed algorithm preserves the outline portion and surface information from the images, which yields perceptible effects. This will be useful in order to take out visual data from a noisy background. Since it is shown that the results with noisy and after denoised compared visually and also parametric analysis is carried out by calculating PSNR, MSE, contrast, structural content, entropy, etc
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