Hemangiopericytoma of the Breast: A Case Report and a Review of the Literature

Introduction. Sarcomas of the breast are rare and hemangiopericytoma (HPC) of the breast is even rarer. Case Report. We report a case of a 43-year-old woman who presented with a 4 cm mass in her right breast. Her family history was positive for breast cancer. A fine needle aspiration indicated a mal...

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Main Authors: Georgios Koukourakis, Evagelos Filopoulos, Kasiani Kapatou, Georgios Zacharias
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:Case Reports in Oncological Medicine
Online Access:http://dx.doi.org/10.1155/2015/210643
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spelling doaj-81a1085e576947459ef4eb9ba3975de22020-11-24T23:21:49ZengHindawi LimitedCase Reports in Oncological Medicine2090-67062090-67142015-01-01201510.1155/2015/210643210643Hemangiopericytoma of the Breast: A Case Report and a Review of the LiteratureGeorgios Koukourakis0Evagelos Filopoulos1Kasiani Kapatou2Georgios Zacharias3Radiation Oncology Department, Saint Savvas Anticancer Institute of Athens, Alexandra’s Avenue 171, 11522 Athens, GreeceBreast Surgery Department, Saint Savvas Anticancer Institute of Athens, Alexandra’s Avenue 171, 11522 Athens, GreeceClinical Pathology Department, Saint Savvas Anticancer Institute of Athens, Alexandra’s Avenue 171, 11522 Athens, GreeceLaboratory of Hematology, Panarcadian General Hospital of Peloponnese, Red Cross Street, 22100 Tripoli, GreeceIntroduction. Sarcomas of the breast are rare and hemangiopericytoma (HPC) of the breast is even rarer. Case Report. We report a case of a 43-year-old woman who presented with a 4 cm mass in her right breast. Her family history was positive for breast cancer. A fine needle aspiration indicated a malignant vascular tumor. An excision biopsy and frozen section analysis confirmed the presence of an encapsulated mesenchymal tumor. Its morphology and immunohistochemical marker profile were characteristic for a malignant hemangiopericytoma. Thus, she underwent a tumor excision without an axilla sampling. Approximately one year after the surgery the patient is well without local recurrence or metastasis disease to be observed. We also reviewed the literature and discuss the treatment options, characteristics, and immunophenotype of HPC. Conclusions. The accurate diagnosis of HPC depends on the appropriate histological and immunohistochemical examination. Surgical resection is the treatment of choice and due to scarcity of cases and unpredictable biological behavior of these tumors long term follow-up may be warranted.http://dx.doi.org/10.1155/2015/210643
collection DOAJ
language English
format Article
sources DOAJ
author Georgios Koukourakis
Evagelos Filopoulos
Kasiani Kapatou
Georgios Zacharias
spellingShingle Georgios Koukourakis
Evagelos Filopoulos
Kasiani Kapatou
Georgios Zacharias
Hemangiopericytoma of the Breast: A Case Report and a Review of the Literature
Case Reports in Oncological Medicine
author_facet Georgios Koukourakis
Evagelos Filopoulos
Kasiani Kapatou
Georgios Zacharias
author_sort Georgios Koukourakis
title Hemangiopericytoma of the Breast: A Case Report and a Review of the Literature
title_short Hemangiopericytoma of the Breast: A Case Report and a Review of the Literature
title_full Hemangiopericytoma of the Breast: A Case Report and a Review of the Literature
title_fullStr Hemangiopericytoma of the Breast: A Case Report and a Review of the Literature
title_full_unstemmed Hemangiopericytoma of the Breast: A Case Report and a Review of the Literature
title_sort hemangiopericytoma of the breast: a case report and a review of the literature
publisher Hindawi Limited
series Case Reports in Oncological Medicine
issn 2090-6706
2090-6714
publishDate 2015-01-01
description Introduction. Sarcomas of the breast are rare and hemangiopericytoma (HPC) of the breast is even rarer. Case Report. We report a case of a 43-year-old woman who presented with a 4 cm mass in her right breast. Her family history was positive for breast cancer. A fine needle aspiration indicated a malignant vascular tumor. An excision biopsy and frozen section analysis confirmed the presence of an encapsulated mesenchymal tumor. Its morphology and immunohistochemical marker profile were characteristic for a malignant hemangiopericytoma. Thus, she underwent a tumor excision without an axilla sampling. Approximately one year after the surgery the patient is well without local recurrence or metastasis disease to be observed. We also reviewed the literature and discuss the treatment options, characteristics, and immunophenotype of HPC. Conclusions. The accurate diagnosis of HPC depends on the appropriate histological and immunohistochemical examination. Surgical resection is the treatment of choice and due to scarcity of cases and unpredictable biological behavior of these tumors long term follow-up may be warranted.
url http://dx.doi.org/10.1155/2015/210643
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AT evagelosfilopoulos hemangiopericytomaofthebreastacasereportandareviewoftheliterature
AT kasianikapatou hemangiopericytomaofthebreastacasereportandareviewoftheliterature
AT georgioszacharias hemangiopericytomaofthebreastacasereportandareviewoftheliterature
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